The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta‐analysis

J Norenhag, J Du, M Olovsson… - … Journal of Obstetrics …, 2020 - Wiley Online Library
Background Persistent infection with high‐risk human papillomavirus can lead to cervical
dysplasia and cancer. Recent studies have suggested associations between the …

The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

[HTML][HTML] Cervicovaginal microbiome and natural history of HPV in a longitudinal study

M Usyk, CP Zolnik, PE Castle, C Porras… - PLoS …, 2020 - journals.plos.org
Background Human papillomavirus (HPV) infection is one of the most common sexually
transmitted infections. However, only a small percentage of high-risk (HR) HPV infections …

[HTML][HTML] Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health

MI Petrova, E Lievens, S Malik, N Imholz… - Frontiers in …, 2015 - frontiersin.org
The human body is colonized by a vast number of microorganisms collectively referred to as
the human microbiota. One of the main microbiota body sites is the female genital tract …

Vaginal dysbiosis and the risk of human papillomavirus and cervical cancer: systematic review and meta-analysis

N Brusselaers, S Shrestha, J Van De Wijgert… - American journal of …, 2019 - Elsevier
Objective The vaginal microbiota proposedly influence the association between human
papillomavirus and cervical cancer. Our aim was to assess whether vaginal dysbiosis affects …

[HTML][HTML] Cervical microbiome and cytokine profile at various stages of cervical cancer: a pilot study

A Audirac-Chalifour, K Torres-Poveda… - PloS one, 2016 - journals.plos.org
Cervical cancer (CC) is caused by high-risk human papillomavirus persistence due to the
immunosuppressive tumor microenvironment mediated by cytokines. Vaginal microbiota …

[HTML][HTML] Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection

M Di Paola, C Sani, AM Clemente, A Iossa, E Perissi… - Scientific reports, 2017 - nature.com
Abstract Changes in cervico-vaginal microbiota with Lactobacillus depletion and increased
microbial diversity facilitate human papillomavirus (HPV) infection and might be involved in …

Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection

RM Brotman, MD Shardell, P Gajer… - The Journal of …, 2014 - academic.oup.com
Background. We sought to describe the temporal relationship between vaginal microbiota
and human papillomavirus (HPV) detection. Methods. Thirty-two reproductive-age women …

Does the vaginal microbiota play a role in the development of cervical cancer?

M Kyrgiou, A Mitra, AB Moscicki - Translational Research, 2017 - Elsevier
Persistent infection with oncogenic human papillomavirus (HPV) is necessary but not
sufficient for the development of cervical cancer. The factors promoting persistence as well …

[HTML][HTML] Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women

P Łaniewski, D Barnes, A Goulder, H Cui, DJ Roe… - Scientific reports, 2018 - nature.com
While high-risk human papillomavirus (HPV) infection is a well-established risk factor for
cervical cancer, there are likely other factors within the local microenvironment that …