Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop
Multiple sclerosis (MS) is an inflammatory and neurodegenerative demyelinating disease of
the central nervous system (CNS), most likely autoimmune in origin, usually beginning in …
the central nervous system (CNS), most likely autoimmune in origin, usually beginning in …
The evidence for a role of B cells in multiple sclerosis
G Disanto, JM Morahan, MH Barnett, G Giovannoni… - Neurology, 2012 - AAN Enterprises
Understanding the pathogenesis of complex immunologic disorders such as multiple
sclerosis (MS) is challenging. Abnormalities in many different cell types are observed in the …
sclerosis (MS) is challenging. Abnormalities in many different cell types are observed in the …
A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches
VV Bashinskaya, OG Kulakova, AN Boyko, AV Favorov… - Human genetics, 2015 - Springer
Multiple sclerosis (MS) is a common complex neurodegenerative disease of the central
nervous system. It develops with autoimmune inflammation and demyelination. Genome …
nervous system. It develops with autoimmune inflammation and demyelination. Genome …
[HTML][HTML] Impact of B cells to the pathophysiology of multiple sclerosis
BM Arneth - Journal of Neuroinflammation, 2019 - Springer
Introduction Multiple sclerosis (MS) is a chronic autoimmune disorder that affects the central
nervous system and compromises the health and well-being of millions of people worldwide …
nervous system and compromises the health and well-being of millions of people worldwide …
Bioinformatic processes for determination of peptide binding
RD Bremel, J Homan - 2013 - Google Patents
This invention relates to the identification of peptide binding to ligands, and in particular to
identification of epitopes expressed by microorganisms and by mammalian cells. The …
identification of epitopes expressed by microorganisms and by mammalian cells. The …
Heterogeneity in multiple sclerosis: scratching the surface of a complex disease
G Disanto, AJ Berlanga, AE Handel… - Autoimmune …, 2011 - Wiley Online Library
Multiple Sclerosis (MS) is the most common demyelinating disease of the central nervous
system. Although the etiology and the pathogenesis of MS has been extensively …
system. Although the etiology and the pathogenesis of MS has been extensively …
Epstein–Barr virus and multiple sclerosis. From evidence to therapeutic strategies
S Fernández-Menéndez, M Fernández-Morán… - Journal of the …, 2016 - Elsevier
Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …
Multiple sclerosis: risk factors and their interactions
G Disanto, JM Morahan… - CNS & Neurological …, 2012 - ingentaconnect.com
Multiple sclerosis (MS) is a highly debilitating immune mediated disorder of the central
nervous system and represents a substantial burden to the developed world. Despite the …
nervous system and represents a substantial burden to the developed world. Despite the …
[HTML][HTML] HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders
Bipolar affective disorder (BD) is a severe psychiatric illness, for which lithium (Li) is the gold
standard for acute and maintenance therapies. The therapeutic response to Li in BD is …
standard for acute and maintenance therapies. The therapeutic response to Li in BD is …
The role of epigenetic mechanisms and processes in autoimmune disorders
JM Greer, PA McCombe - Biologics: Targets and Therapy, 2012 - Taylor & Francis
The lack of complete concordance of autoimmune disease in identical twins suggests that
nongenetic factors play a major role in determining disease susceptibility. In this review, we …
nongenetic factors play a major role in determining disease susceptibility. In this review, we …