Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach

R Murugan, R Rajesh, B Seenivasan… - Microbial …, 2022 - Elsevier
Infections due to multidrug-resistant Pseudomonas aeruginosa are prevalent among
patients with cystic fibrosis. The emergence of antibiotic-resistant pathogens necessitated …

[HTML][HTML] Aquatic Peptide: The Potential Anti-Cancer and Anti-Microbial Activity of GE18 Derived from Pathogenic Fungus Aphanomyces invadans

M Velayutham, PS Priya, P Sarkar, R Murugan… - Molecules, 2023 - mdpi.com
Small molecules as well as peptide-based therapeutic approaches have attracted global
interest due to their lower or no toxicity in nature, and their potential in addressing several …

Histone acetyltransferases derived RW20 protects and promotes rapid clearance of Pseudomonas aeruginosa in zebrafish larvae

A Guru, R Murugan, J Arockiaraj - International Microbiology, 2024 - Springer
Pseudomonas is a group of bacteria that can cause a wide range of infections, particularly in
people with weakened immune systems, such as those with cystic fibrosis or who are …

Azadiradione (AZD), neem biomass derived limonoid extraction, characterization, potential biological activities with special reference to anti-microbial and anti-cancer …

PS Priya, RS Kumar, MRA Gawwad, KM Alarjani… - South African Journal of …, 2023 - Elsevier
The resistance of conventional drugs to bacterial infections and cancer poses a significant
threat to the healthcare system causing increased mortality. Metabolites derived from plant …

DbGTi: Thermostable trypsin inhibitor from Dioscorea bulbifera L. ground tubers: assessment of antioxidant and antibacterial properties and cytotoxicity evaluation …

S Jegadheeshwari, M Velayutham… - International Journal of …, 2024 - Elsevier
Oxidative stress disorders and diseases caused by drug-resistant bacteria have emerged as
significant public health concerns. Plant-based medications like protease inhibitors are …

Antibacterial Effect of a Short Peptide, VV18, from Calcineurin-A of Macrobrachium rosenbergii: Antibiofilm Agent Against Escherichia coli and a Bacterial Membrane Disruptor …

G Ravichandran, P Sarkar, TW Chen… - International Journal of …, 2022 - Springer
We have reported the molecular function of Calcineurin A (Caln-A) identified from an earlier
developed cDNA library of Macrobrachium rosenbergii (Mr). The antimicrobial function of Mr …