Invasive lobular carcinoma accounts for 5%–15% of all invasive breast cancers, with a
marked increase in incidence rates over the past two decades. Distinctive biological …

Breast cancer is the second leading cause of cancer related deaths in women. It is therefore
important to understand the mechanisms underlying breast cancer development as well as …

Purpose: We queried whether comprehensive genomic profiling using a next-generation
sequencing–based assay could identify novel and unanticipated targets of therapy for …

Background The surgical management of lobular in-situ neoplasia (LN) identified by core
needle biopsy (CNB) is currently variable. Our institution has routinely excised LN on CNB …

Invasive lobular carcinoma is the second most common histologic form of breast cancer,
representing 5% to 15% of all invasive breast cancers. Due to an insidious proliferative …

Invasive lobular carcinoma (ILC) of the breast, characterized by loss of E‐cadherin
expression, accounts for 5–15% of invasive breast cancers and it is believed to arise via a …

Comparing risk factor associations between invasive breast cancers and possible
precursors may further our understanding of factors related to initiation versus progression …

Background Lobular carcinomas in situ (LCIS) represent 1-2% of all breast cancers. Both
significance and treatment remain widely debated, as well as the possible similarities with …

Background Using new molecular biology techniques, recent studies have implicated a
common evolutionary pathway between lobular neoplasia, lobular carcinomas, and …

Abstract Purpose of Review To present current data on histopathologic types, imaging
presentation, and management of lobular neoplasia of the breast. Recent Findings Non …