Cannabidiol's (CBD) safety profile and broad action has made it a popular treatment option
for anxiety and co-occurring sleep disturbance. However, its efficacy in healthy and clinical …

Background Although pre-clinical experiments associate cannabinoids with reduced
depressive symptoms, there is a paucity of clinical evidence. This study aims to analyze the …

Given that available antidepressant pharmacotherapies are not optimally effective, there is a
need for alternative treatment options that are rooted in a comprehensive understanding of …

Background Cannabis contains hundreds of chemical constituents beyond delta-9-
tetrahydrocannabinol (THC), which is believed to drive most of its acute pharmacodynamic …

Objective Expanding access to legal cannabis has dovetailed with increased interest in
medical cannabis (MC) use; however, there is a paucity of research examining MC use to …

Sleep is an essential biological phase of our daily life cycle and is necessary for maintaining
homeostasis, alertness, metabolism, cognition, and other key functions across the animal …

Major depressive disorder and major depressive episodes (MDD/MDE) are characterized by
the activation of the immune–inflammatory response system (IRS) and the compensatory …

Introduction There is growing evidence on the efficacy of cannabis-based medicinal
products (CBMPs) for chronic pain (CP). Due to the interaction between CP and anxiety, and …

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis
users. Methods: An anonymous online survey collected demographics, health information …

While many drugs are used exclusively for medical reasons, and others are used solely for
recreation, some drugs are commonly used for both purposes. For example, cannabis …