Branch management: mechanisms of axon branching in the developing vertebrate CNS
The remarkable ability of a single axon to extend multiple branches and form terminal arbors
enables vertebrate neurons to integrate information from divergent regions of the nervous …
enables vertebrate neurons to integrate information from divergent regions of the nervous …
[HTML][HTML] Rethinking stereotypies in autism
MJ McCarty, AC Brumback - Seminars in pediatric neurology, 2021 - Elsevier
ABSTRACT Stereotyped movements (“stereotypies”) are semi-voluntary repetitive
movements that are a prominent clinical feature of autism spectrum disorder. They are …
movements that are a prominent clinical feature of autism spectrum disorder. They are …
[HTML][HTML] Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis
M Spillane, A Ketschek, TT Merianda, JL Twiss, G Gallo - Cell reports, 2013 - cell.com
The branching of axons is a fundamental aspect of nervous system development and
neuroplasticity. We report that branching of sensory axons in the presence of nerve growth …
neuroplasticity. We report that branching of sensory axons in the presence of nerve growth …
[图书][B] What biological functions are and why they matter
J Garson - 2019 - books.google.com
The biological functions debate is a perennial topic in the philosophy of science. In the first
full-length account of the nature and importance of biological functions for many years …
full-length account of the nature and importance of biological functions for many years …
microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons
The capacity of neurons to develop a long axon and multiple dendrites defines neuron
connectivity in the CNS. The highly conserved microRNA-9 (miR-9) is expressed in both …
connectivity in the CNS. The highly conserved microRNA-9 (miR-9) is expressed in both …
[HTML][HTML] Primary cilia signaling promotes axonal tract development and is disrupted in Joubert syndrome-related disorders models
Appropriate axonal growth and connectivity are essential for functional wiring of the brain.
Joubert syndrome-related disorders (JSRD), a group of ciliopathies in which mutations …
Joubert syndrome-related disorders (JSRD), a group of ciliopathies in which mutations …
[HTML][HTML] Septin-driven coordination of actin and microtubule remodeling regulates the collateral branching of axons
Axon branching is fundamental to the development of the peripheral and central nervous
system [1, 2]. Branches that sprout from the axon shaft are termed collateral or interstitial …
system [1, 2]. Branches that sprout from the axon shaft are termed collateral or interstitial …
Three-dimensional evaluation of retinal ganglion cell axon regeneration and pathfinding in whole mouse tissue after injury
X Luo, Y Salgueiro, SR Beckerman, VP Lemmon… - Experimental …, 2013 - Elsevier
Injured retinal ganglion cell (RGC) axons do not regenerate spontaneously, causing loss of
vision in glaucoma and after trauma. Recent studies have identified several strategies that …
vision in glaucoma and after trauma. Recent studies have identified several strategies that …
[HTML][HTML] The multifaceted roles of primary cilia in the development of the cerebral cortex
K Hasenpusch-Theil, T Theil - Frontiers in cell and developmental …, 2021 - frontiersin.org
The primary cilium, a microtubule based organelle protruding from the cell surface and
acting as an antenna in multiple signaling pathways, takes center stage in the formation of …
acting as an antenna in multiple signaling pathways, takes center stage in the formation of …
[HTML][HTML] Mathematical models of neuronal growth
The establishment of a functioning neuronal network is a crucial step in neural development.
During this process, neurons extend neurites—axons and dendrites—to meet other neurons …
During this process, neurons extend neurites—axons and dendrites—to meet other neurons …