Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Combatting antibiotic-resistant bacteria using nanomaterials

A Gupta, S Mumtaz, CH Li, I Hussain… - Chemical Society …, 2019 - pubs.rsc.org
The dramatic increase in antimicrobial resistance for pathogenic bacteria constitutes a key
threat to human health. The Centers for Disease Control and Prevention has recently stated …

Biofilm‐sensitive photodynamic nanoparticles for enhanced penetration and antibacterial efficiency

S Wu, C Xu, Y Zhu, L Zheng, L Zhang… - Advanced Functional …, 2021 - Wiley Online Library
Efficient antimicrobials are urgently needed for the treatment of bacterial biofilms due to their
resistance to traditional drugs. Photodynamic therapy (PDT) is a new strategy that has been …

Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations

NE Eleraky, A Allam, SB Hassan, MM Omar - Pharmaceutics, 2020 - mdpi.com
Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Size and charge adaptive clustered nanoparticles targeting the biofilm microenvironment for chronic lung infection management

Y Gao, J Wang, M Chai, X Li, Y Deng, Q Jin, J Ji - ACS nano, 2020 - ACS Publications
Chronic lung infection caused by bacterial biofilms is an extremely serious clinical problem,
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …

Combined antioxidant–antibiotic treatment for effectively healing infected diabetic wounds based on polymer vesicles

T Wang, Y Li, EJ Cornel, C Li, J Du - ACS nano, 2021 - ACS Publications
Infected diabetic wounds are difficult to heal due to high reactive oxygen species (ROS)
concentrations and recurrent infections. Such wounds can easily deteriorate into a diabetic …

Tailoring supramolecular short peptide nanomaterials for antibacterial applications

M Abbas, M Ovais, A Atiq, TM Ansari, R Xing… - Coordination Chemistry …, 2022 - Elsevier
The rise of bacterial resistance to current antibiotics poses a threat to humanity and
reinforces the need for new-generation nanomaterials with antibacterial properties and …

Bacteria-responsive biomimetic selenium nanosystem for multidrug-resistant bacterial infection detection and inhibition

A Lin, Y Liu, X Zhu, X Chen, J Liu, Y Zhou, X Qin, J Liu - Acs Nano, 2019 - ACS Publications
Multidrug-resistant (MDR) bacterial infections are a severe threat to public health owing to
their high risk of fatality. Noticeably, the premature degradation and undeveloped imaging …

Dual stimuli-responsive metal-organic framework-based nanosystem for synergistic photothermal/pharmacological antibacterial therapy

Y Xiao, M Xu, N Lv, C Cheng, P Huang, J Li, Y Hu… - Acta Biomaterialia, 2021 - Elsevier
The serious threat of drug-resistant bacterial pathogens has arisen through overuse of
antibiotics. Photothermal therapy (PTT) has come to prominence as viable alternative …

Ag nanoparticles cluster with pH‐triggered reassembly in targeting antimicrobial applications

X Xie, TC Sun, J Xue, Z Miao, X Yan… - Advanced Functional …, 2020 - Wiley Online Library
Antibacterial efficiency can be effectively improved by applying targeting antibacterial
materials and strategies. Herein, the successful synthesis of uniform pH‐responsive Ag …