[HTML][HTML] An overview of systemic lupus erythematosus (SLE) pathogenesis, classification, and management

MA Ameer, H Chaudhry, J Mushtaq, OS Khan, M Babar… - Cureus, 2022 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …

Production of monoclonal antibodies for therapeutic purposes: A review

W Alejandra, JPM Irene, GSF Antonio… - International …, 2023 - Elsevier
Monoclonal antibodies (mAbs) have been used in the development of immunotherapies that
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …

[HTML][HTML] Autoimmune pemphigus: latest advances and emerging therapies

YL Lim, G Bohelay, S Hanakawa, P Musette… - Frontiers in Molecular …, 2022 - frontiersin.org
Pemphigus represents a group of rare and severe autoimmune intra-epidermal blistering
diseases affecting the skin and mucous membranes. These painful and debilitating diseases …

Current insights on biomarkers in lupus nephritis: A systematic review of the literature

L Palazzo, J Lindblom, C Mohan, I Parodis - Journal of Clinical Medicine, 2022 - mdpi.com
Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

The shared biomarkers and pathways of systemic lupus erythematosus and metabolic syndrome analyzed by bioinformatics combining machine learning algorithm …

Y Wang, Z Huang, Y Xiao, W Wan, X Yang - Frontiers in Immunology, 2022 - frontiersin.org
Background Systemic lupus erythematosus (SLE) is one of the most prevalent systemic
autoimmune diseases, and metabolic syndrome (MetS) is the most common metabolic …

Oxidative stress contributes to inflammatory and cellular damage in systemic lupus erythematosus: cellular markers and molecular mechanism

Z Yan, Q Chen, Y Xia - Journal of Inflammation Research, 2023 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease with complex
pathogenesis, the treatment of which relies exclusively on the use of immunosuppressants …

Endothelial function and endothelial progenitor cells in systemic lupus erythematosus

A Mak, JKY Chan - Nature Reviews Rheumatology, 2022 - nature.com
The observations that traditional cardiovascular disease (CVD) risk factors fail to fully
account for the excessive cardiovascular mortality in patients with systemic lupus …

Belimumab or anifrolumab for systemic lupus erythematosus? A risk-benefit assessment

KA Kirou, M DallEra, C Aranow, HJ Anders - Frontiers in Immunology, 2022 - frontiersin.org
Treatment of systemic lupus erythematosus (SLE) currently employs agents with relatively
unselective immunosuppressive properties. However, two target-specific biological drugs …

Considerations for novel COVID-19 mucosal vaccine development

W Alturaiki - Vaccines, 2022 - mdpi.com
Mucosal surfaces are the first contact sites of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Most SARS-CoV-2 vaccines induce specific IgG responses …

Circulating and skin biopsy-present cytokines related to the pathogenesis of cutaneous lupus erythematosus

V Erazo-Martínez, GJ Tobón, CA Cañas - Autoimmunity Reviews, 2023 - Elsevier
Cutaneous lupus erythematosus (CLE) is a common disease that may appear as a separate
entity from systemic lupus erythematosus (SLE), precede SLE development, or occur as a …