Early life stress is associated with long-term and pervasive adverse effects on
neuroendocrine development, affecting normal cognitive and emotional development …

The excitatory-to-inhibitory functional switch of γ-aminobutyric acid (GABA; GABA switch),
which normally occurs in the first to the second postnatal week in the hippocampus, is …

There is a relative consensus about the detrimental impact of childhood maltreatment on
later mental health problems and behavioral difficulties. Prior research suggests that …

Environmental Enrichment (EE) is based on the promotion of socio-environmental stimuli,
which mimic favorable environmental conditions for the practice of physical activity and …

Neuro-ethological studies conducted by Panksepp and his colleagues have provided an
understanding of how the activity of the mesolimbic dopaminergic (ML DA) system leads to …

Psychiatric disorders such as anxiety, depression and addiction are often comorbid brain
pathologies thought to share common mechanistic biology. As part of the cortico-limbic …

Environmental enrichment (EE) has been successfully implemented in human rehabilitation
settings. However, the mechanisms underlying its success are not understood. Incorporating …

Environmental enrichment is a widely used experimental manipulation that consistently
shows measurable effects on rodent behaviour across the lifespan. This scoping review …

Significant loss produces the highest degree of stress and compromised well-being in
humans. Current rodent models of stress involve the application of physically or …

Antagonist and long-lasting environmental manipulations (EM) have successfully induced or
reduced the stress responses and quality of life of zebrafish. For instance, environmental …