Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

N-Containing tricyclic compounds, especially the tricyclic N-heterocycles, are important
structural motifs that possess significant potential in organic chemistry for their momentous …

Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

Inflammatory bowel disease (IBD) represents a group of intestinal disorders with self-
destructive and chronic inflammation in the digestive tract, requiring long-term medications …

Novel axially chiral biphenyl diphosphine ligands E nm-BridgePhos, bearing an ether chain
bridge at the 5, 5′-position of the biphenyl backbone, have been developed and …

During drug discovery programmes, medicinal chemists rely on compounds derived from
Haber ammonia as the source of this clinically important nitrogen heteroatom and as a …

Nitrogen-containing heteroaromatic cores are ubiquitous building blocks in organic
chemistry. Herein, we present a family of metal-free intermolecular formal cycloaddition …

Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …

Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis.
Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects and that …