The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …

CNS border-associated macrophages (BAMs) are a small population of specialised
macrophages localised in the choroid plexus, meningeal and perivascular spaces. Until …

Translational neuroscience is a multidisciplinary field that aims to bridge the gap between
basic science and clinical practice. Regarding aphasia rehabilitation, there are still several …

As a leading cause of mortality and morbidity, stroke constitutes a significant global health
burden. Ischemic stroke accounts for 80% of cases and occurs due to an arterial thrombus …

Background multiple sclerosis (MS) is a complex disease sustained by several pathogenic
mechanisms. As such, combination therapy strategies, targeting a range of disease …

Ischemic stroke is the third leading cause of mortality worldwide, but its medical
management is still limited to the use of thrombolytics as a lifesaving option. Multiple …

Stroke volume is a key determinant of infarct severity and an important metric for evaluating
treatments. However, accurate estimation of stroke volume can be challenging, due to the …

Despite great advances in acute care and rehabilitation, stroke remains the leading cause of
motor impairment in the industrialized world. We have developed a deep brain stimulation …

Background Acute ischemic stroke (AIS) is a common cerebrovascular event associated with
high incidence, disability, and poor prognosis. Studies have shown that various cell types …

Background Sanguinate, a bovine PEGylated carboxyhemoglobin-based oxygen carrier
with vasodilatory, oncotic and anti-inflammatory properties designed to release oxygen in …