[HTML][HTML] TAB182 regulates glycolytic metabolism by controlling LDHA transcription to impact tumor radiosensitivity

S Chen, DF Xie, S Li, J Luo, Y Han, H Guo, S Gao… - Cell Death & …, 2024 - nature.com
Metabolic reprogramming, a hallmark of cancer, is closely associated with tumor
development and progression. Changes in glycolysis play a crucial role in conferring …

Mapping multi-omics characteristics related to short-term PM2. 5 trajectory and their impact on type 2 diabetes in middle-aged and elderly adults in Southern China

J Wang, W Hu, Z Xue, X Cai, S Zhang, F Li, L Lin… - Journal of Hazardous …, 2024 - Elsevier
The relationship between PM 2.5 and metabolic diseases, including type 2 diabetes (T2D),
has become increasingly prominent, but the molecular mechanism needs to be further …

MiR-3682-3p promotes esophageal cancer progression by targeting FHL1 and activating the Wnt/β-catenin signaling pathway

Y Cai, L Xia, H Zhu, H Cheng, Y Tian, L Sun, J Wang… - Cellular …, 2024 - Elsevier
Background Esophageal cancer (EC) is highly ranked among all cancers in terms of its
incidence and mortality rates. MicroRNAs (miRNAs) are considered to play key regulatory …

[HTML][HTML] Downregulation of TAB182 promotes cancer stem-like cell properties and therapeutic resistance in triple-negative breast cancer cells

H He, S Wang, W Zhang, S Gao, H Guan, P Zhou - BMC cancer, 2023 - Springer
TAB182 participates in DNA damage repair and radio-/chemosensitivity regulation in
various tumors, but its role in tumorigenesis and therapeutic resistance in breast cancer …

[HTML][HTML] Hsa_circ_0001615 downregulation inhibits esophageal cancer development through miR-142-5p/β-catenin

Y Dai, Q Xu, M Xia, C Chen, X Xiong, X Yang, W Wang - PeerJ, 2024 - peerj.com
Background Recent studies have found that circular RNAs (circRNAs) play important roles in
tumorigenesis. This study aimed to determine the function and potential mechanisms of …

[HTML][HTML] Promotion of non-small cell lung cancer tumor growth by FHL2 via inducing angiogenesis and vascular permeability

T Chen, J Chen, Q Chen, Z Liang, L Pan… - Journal of Thoracic …, 2024 - jtd.amegroups.org
Background: Antiangiogenetic therapy is one of the effective strategies for non-small cell
lung cancer (NSCLC) treatment. Four-and-a-half LIM-domain protein 2 (FHL2) serves as a …