Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

Research in the field of ischemia-reperfusion injury continues to be plagued by the inability
to translate research findings to clinically useful therapies. This may in part relate to the …

Events during ischemia/reperfusion (I/R) injury include: neutrophil‐mediated endothelial
cytotoxicity and activation, generation of free radicals, triggering of cytokines and …

Abstract Ischemia-reperfusion (I/R) injury is a common clinical event with the potential to
seriously affect, and sometimes kill, the patient. Interruption of blood supply causes …

The complement system is an essential part of innate immunity, typically conferring
protection via eliminating pathogens and accumulating debris. However, the defensive …

Sepsis and systemic inflammatory response syndrome (SIRS) are associated with an
exacerbated production of both pro-and anti-inflammatory mediators that are mainly …

Human intestinal ischemia-reperfusion (IR) is a frequent phenomenon carrying high
morbidity and mortality. Although intestinal IR-induced inflammation has been studied …

Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

Tissue and organ replacement have quickly outpaced available supply. Tissue
bioengineering holds the promise for additional tissue availability. Various scaffolds are …

The mannose-binding lectin (MBL), a circulating pattern recognition molecule, recognizes a
wide range of infectious agents with resultant initiation of the complement cascade in an Ab …