Pathogenesis of Candida albicans biofilm

C Tsui, EF Kong, MA Jabra-Rizk - FEMS Pathogens and …, 2016 - academic.oup.com
Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …

The Candida pathogenic species complex

SA Turner, G Butler - Cold Spring Harbor …, 2014 - perspectivesinmedicine.cshlp.org
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease

I Doron, M Mesko, XV Li, T Kusakabe, I Leonardi… - Nature …, 2021 - nature.com
Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by
shaping the resident microbiota community, restricting the growth of bacterial pathogens and …

Commensal protection of Staphylococcus aureus against antimicrobials by Candida albicans biofilm matrix

EF Kong, C Tsui, S Kucharíková, D Andes, P Van Dijck… - MBio, 2016 - Am Soc Microbiol
Biofilm-associated polymicrobial infections, particularly those involving fungi and bacteria,
are responsible for significant morbidity and mortality and tend to be challenging to treat …

Studying fungal pathogens of humans and fungal infections: Fungal diversity and diversity of approaches

G Janbon, J Quintin, F Lanternier, C d'Enfert - Microbes and Infection, 2019 - Elsevier
Abstract Seminal work by Louis Pasteur revealed the contribution of fungi–yeasts and
microsporidia to agroindustry and disease in animals, respectively. More than 150 years …

Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

T Schwarzmueller, B Ma, E Hiller, F Istel… - PLoS …, 2014 - journals.plos.org
The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis,
causing infections ranging from superficial to life-threatening disseminated disease. The …

Cell wall remodeling enzymes modulate fungal cell wall elasticity and osmotic stress resistance

IV Ene, LA Walker, M Schiavone, KK Lee… - MBio, 2015 - Am Soc Microbiol
The fungal cell wall confers cell morphology and protection against environmental insults.
For fungal pathogens, the cell wall is a key immunological modulator and an ideal …

The dynamic fungal genome: polyploidy, aneuploidy and copy number variation in response to stress

P Vande Zande, X Zhou… - Annual review of …, 2023 - annualreviews.org
Fungal species have dynamic genomes and often exhibit genomic plasticity in response to
stress. This genome plasticity often comes with phenotypic consequences that affect fitness …

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

TR O'Meara, K Duah, CX Guo, ME Maxson, RG Gaudet… - MBio, 2018 - Am Soc Microbiol
The innate immune system is the first line of defense against invasive fungal infections. As a
consequence, many successful fungal pathogens have evolved elegant strategies to interact …

Metabolic modeling predicts specific gut bacteria as key determinants for Candida albicans colonization levels

MH Mirhakkak, S Schäuble, TE Klassert… - The ISME …, 2021 - academic.oup.com
Candida albicans is a leading cause of life-threatening hospital-acquired infections and can
lead to Candidemia with sepsis-like symptoms and high mortality rates. We reconstructed a …