Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation
C Lemberg, K Martinez de San Vicente… - PLoS …, 2022 - journals.plos.org
As part of the human microbiota, the fungus Candida albicans colonizes the oral cavity and
other mucosal surfaces of the human body. Commensalism is tightly controlled by complex …
other mucosal surfaces of the human body. Commensalism is tightly controlled by complex …
Clinical implications of oral candidiasis: host tissue damage and disseminated bacterial disease
EF Kong, S Kucharíková, P Van Dijck… - Infection and …, 2015 - Am Soc Microbiol
The clinical significance of polymicrobial interactions, particularly those between commensal
species with high pathogenic potential, remains largely understudied. Although the …
species with high pathogenic potential, remains largely understudied. Although the …
Gymnemic Acids Inhibit Hyphal Growth and Virulence in Candida albicans
G Vediyappan, V Dumontet, F Pelissier, C d'Enfert - PloS one, 2013 - journals.plos.org
Candida albicans is an opportunistic and polymorphic fungal pathogen that causes
mucosal, disseminated and invasive infections in humans. Transition from the yeast form to …
mucosal, disseminated and invasive infections in humans. Transition from the yeast form to …
DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway
J MacAlpine, Z Liu, S Hossain, L Whitesell, N Robbins… - MBio, 2023 - Am Soc Microbiol
Candida albicans is an opportunistic human fungal pathogen that causes common
superficial mycoses in healthy populations and invasive disease in immunocompromised …
superficial mycoses in healthy populations and invasive disease in immunocompromised …
From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis
V Basso, C d'Enfert, S Znaidi… - Fungal Physiology and …, 2019 - Springer
Candida albicans is a commensal yeast of most healthy individuals, but also one of the most
prevalent human fungal pathogens. During adaptation to the mammalian host, C. albicans …
prevalent human fungal pathogens. During adaptation to the mammalian host, C. albicans …
Advances in fungal chemical genomics for the discovery of new antifungal agents
Invasive fungal infections have escalated from a rare curiosity to a major cause of human
mortality around the globe. This is in part due to a scarcity in the number of antifungal drugs …
mortality around the globe. This is in part due to a scarcity in the number of antifungal drugs …
A Comprehensive Functional Portrait of Two Heat Shock Factor-Type Transcriptional Regulators Involved in Candida albicans Morphogenesis and Virulence
S Znaidi, A Nesseir, M Chauvel, T Rossignol… - PLoS …, 2013 - journals.plos.org
Sfl1p and Sfl2p are two homologous heat shock factor-type transcriptional regulators that
antagonistically control morphogenesis in Candida albicans, while being required for full …
antagonistically control morphogenesis in Candida albicans, while being required for full …
Hypoxia and Temperature Regulated Morphogenesis in Candida albicans
PR Desai, L van Wijlick, D Kurtz, M Juchimiuk… - PLoS …, 2015 - journals.plos.org
Candida albicans is a common commensal in the human gut but in predisposed patients it
can become an important human fungal pathogen. As a commensal, C. albicans adapts to …
can become an important human fungal pathogen. As a commensal, C. albicans adapts to …
[HTML][HTML] Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models
S Amorim-Vaz, E Delarze, F Ischer… - Frontiers in …, 2015 - frontiersin.org
The aim of the present study was to identify Candida albicans transcription factors (TFs)
involved in virulence. Although mice are considered the gold-standard model to study fungal …
involved in virulence. Although mice are considered the gold-standard model to study fungal …
Targeted Changes of the Cell Wall Proteome Influence Candida albicans Ability to Form Single- and Multi-strain Biofilms
Biofilm formation is an important virulence trait of the pathogenic yeast Candida albicans.
We have combined gene overexpression, strain barcoding and microarray profiling to …
We have combined gene overexpression, strain barcoding and microarray profiling to …