A student's guide to neural circuit tracing

C Saleeba, B Dempsey, S Le, A Goodchild… - Frontiers in …, 2019 - frontiersin.org
The mammalian nervous system is comprised of a seemingly infinitely complex network of
specialized synaptic connections that coordinate the flow of information through it. The field …

A systematic review of direct outputs from the cerebellum to the brainstem and diencephalon in mammals

M Novello, LWJ Bosman, CI De Zeeuw - The Cerebellum, 2024 - Springer
The cerebellum is involved in many motor, autonomic and cognitive functions, and new
tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously …

Inferring neuron-neuron communications from single-cell transcriptomics through NeuronChat

W Zhao, KG Johnston, H Ren, X Xu, Q Nie - Nature communications, 2023 - nature.com
Neural communication networks form the fundamental basis for brain function. These
communication networks are enabled by emitted ligands such as neurotransmitters, which …

Flexible inhibitory control of visually evoked defensive behavior by the ventral lateral geniculate nucleus

A Fratzl, AM Koltchev, N Vissers, YL Tan… - Neuron, 2021 - cell.com
Animals can choose to act upon, or to ignore, sensory stimuli, depending on circumstance
and prior knowledge. This flexibility is thought to depend on neural inhibition, through …

[HTML][HTML] Upgrading the physiological relevance of human brain organoids

A Del Dosso, JP Urenda, T Nguyen, G Quadrato - Neuron, 2020 - cell.com
The recent advent of human pluripotent stem cell (PSC)-derived 3D brain organoids has
opened a window into aspects of human brain development that were not accessible before …

Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures

AL Ludwig, SJ Mayerl, Y Gao… - Proceedings of the …, 2023 - National Acad Sciences
Human pluripotent stem cell (hPSC)-derived retinal organoids (ROs) can efficiently and
reproducibly generate retinal neurons that have potential for use in cell replacement …

Viral tools for neural circuit tracing

Q Liu, Y Wu, H Wang, F Jia, F Xu - Neuroscience bulletin, 2022 - Springer
Neural circuits provide an anatomical basis for functional networks. Therefore, dissecting the
structure of neural circuits is essential to understanding how the brain works. Recombinant …

Myricetin inhibits pseudorabies virus infection through direct inactivation and activating host antiviral defense

H Hu, Z Hu, Y Zhang, H Wan, Z Yin, L Li… - Frontiers in …, 2022 - frontiersin.org
Myricetin, a polyhydroxyflavone compound, is one of the main ingredients of various human
foods and therefore also known as dietary flavonoids. Due to the continuous emergence of …

Brain-wide screen of prelimbic cortex inputs reveals a functional shift during early fear memory consolidation

L Dixsaut, J Gräff - Elife, 2022 - elifesciences.org
Memory formation and storage rely on multiple interconnected brain areas, the contribution
of which varies during memory consolidation. The medial prefrontal cortex, in particular the …

Structure and Function of Neuronal Circuits Linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area

K Prokofeva, YC Saito, Y Niwa, S Mizuno… - Journal of …, 2023 - Soc Neuroscience
To understand how sleep-wakefulness cycles are regulated, it is essential to disentangle
structural and functional relationships between the preoptic area (POA) and lateral …