Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

In this Seminar we discuss developments from the past 5 years in the diagnosis,
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …

We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

Cognitive abnormalities are a core feature of depression, and biases toward negatively
toned emotional information are common, but are they a cause or a consequence of …

Pharmacogenetics (PGx) has the potential to personalize pharmaceutical treatments. Many
relevant gene–drug associations have been discovered, but PGx-guided treatment needs to …

Major depressive disorder (MDD) is a common psychiatric illness with high levels of
morbidity and mortality. Despite intensive research during the past several decades, the …

BACKGROUND: We evaluated the magnitude of the reported associations between
amygdala activation and the serotonin transporter gene linked polymorphic region (5 …