O impacto dos defeitos congênitos no Brasil vem aumentando progressivamente, tendo
passado da quinta para a segunda causa dos óbitos em menores de um ano entre 1980 e …

Purpose Findings from genomic sequencing can have important implications for patients
and family members. Yet, when a patient does not consent to the disclosure of genetic …

South Africa is a developing middle-income country with a population of over 49 million
people. It has a health system, based on national, provincial and private health programmes …

Genetic screening and health-care guidelines recommend that programmes should facilitate
informed choice. It is therefore important that accurate measures of informed choice are …

The serious form of alpha‐1‐antitrypsin deficiency (ATD) Pi ZZ strongly predisposes the
individual for pulmonary emphysema and premature death in adulthood, especially if …

Genetic testing is a powerful technology that enables prediction of future health status.
Testing for cancer-predisposition genes provides information for both the individual and his …

To identify Chinese geneticists' views of ethical issues in genetic testing and screening, a
national survey was conducted. Of 402 Chinese geneticists asked to participate, 255 (63%) …

Advances in medical technology such as those linked to the human genome project are
increasing the potential for predictive testing for a wide range of health threats. There have …

Over the past 9 years we counseled 55 couples whose unborn child was found to carry a
sex chromosome polysomy. We performed a survey of postcounseling parental decisions …

Attitudes towards ethical, legal and social issues in genetic research and practice were
investigated in 402 genetic services providers from 30 provinces and autonomous regions in …