Multiple sclerosis is a chronic, demyelinating disease of the CNS. Cognitive impairment is a
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …

In most cases, multiple sclerosis (MS) begins with a relapsing-remitting course followed by
insidious disability worsening that is independent from clinically apparent relapses and is …

Background The monoclonal antibody ublituximab enhances antibody-dependent cellular
cytolysis and produces B-cell depletion. Ublituximab is being evaluated for the treatment of …

Methods Specific studies and articles were reviewed to illustrate what the test measures, to
evaluate its sensitivity to change, and to discuss its use in clinical practice. Results The …

Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis
(MS), especially deficits in episodic memory and processing speed. The field aims to (1) …

Purpose: To promote understanding of cognitive impairment in multiple sclerosis (MS),
recommend optimal screening, monitoring, and treatment strategies, and address barriers to …

Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …

Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …

Background: The need for more robust outcomes in multiple sclerosis (MS) clinical trials has
been a main priority of the field for decades. Dissatisfaction with existing measures has led …

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous
system, leading to neurodegeneration and manifesting as a variety of symptoms. These can …