In the last years, there has been a significant growth in the literature exploring the
pathophysiology of vascular cognitive impairment (VCI). As an “umbrella term” …

Given the essential role of the blood-brain barrier (BBB) in the central nervous system
(CNS), cumulative investigations have been performed to elucidate how modulation of BBB …

Many people living with dementia and cognitive impairment have dysfunctional
mitochondrial and insulin-glucose metabolism resembling type 2 diabetes mellitus and old …

Резюме Сосудистые когнитивные расстройства (СКР) являются одной из актуальных
проблем клинической неврологии и второй наиболее распространенной причиной …

Cerebral small vessel diseases (SVD) have been causally correlated with ischemic strokes,
leading to cognitive decline and vascular dementia. Neuroimaging and molecular genetic …

Alterations to the cerebral microcirculation have been recognized to play a crucial role in the
development of neurodegenerative disorders. However, the exact role of the microvascular …

Aims In this study, we investigate the effect and underlying mechanism of hyperbaric oxygen
(HBO) treatment on a model of repeated cerebral ischemia-reperfusion injury (IR). Main …

Abstract Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to the pulmonary …

Vascular dementia (VD) is the second largest type of dementia after Alzheimer's disease. At
present, the pathogenesis is complex and there is no effective treatment. Floralozone has …

Dementia has been faced with significant public health challenges and economic burdens
that urges the need to develop safe and effective interventions. In recent years, an …