[HTML][HTML] The important roles of steroid sulfatase and sulfotransferases in gynecological diseases

TL Rižner - Frontiers in pharmacology, 2016 - frontiersin.org
Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and
gynecological cancers including endometrial cancer and ovarian cancer, affect a large …

Estrogen biosynthesis, phase I and phase II metabolism, and action in endometrial cancer

TL Rižner - Molecular and cellular endocrinology, 2013 - Elsevier
Endometrial cancer is the most common gynecological malignancy in the developed World.
Based on their histopathology, clinical manifestation, and epidemiology, the majority of …

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination

C Korch, MA Spillman, TA Jackson, BM Jacobsen… - Gynecologic …, 2012 - Elsevier
OBJECTIVES: Cell lines derived from human ovarian and endometrial cancers, and their
immortalized non-malignant counterparts, are critical tools to investigate and characterize …

Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma

RR Broaddus, HT Lynch, L Chen, MS Daniels… - Cancer, 2006 - Wiley Online Library
BACKGROUND Endometrial carcinoma is a common malignancy in hereditary
nonpolyposis colorectal carcinoma (HNPCC). Like colon carcinoma, endometrial carcinoma …

High Twist expression is involved in infiltrative endometrial cancer and affects patient survival

S Kyo, J Sakaguchi, S Ohno, Y Mizumoto, Y Maida… - Human pathology, 2006 - Elsevier
Epithelial-mesenchymal transition (EMT) is critical not only for morphogenesis during
embryonic development but also the conversion of early-stage tumors into infiltrative …

Successful immortalization of endometrial glandular cells with normal structural and functional characteristics

S Kyo, M Nakamura, T Kiyono, Y Maida… - The American journal of …, 2003 - Elsevier
The human endometrium is a dynamic tissue, the proliferative activity of which dramatically
changes throughout the menstrual cycle, with exquisite regulation by sex-steroid hormones …

AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer

TL Rižner, T Šmuc, R Rupreht, J Šinkovec… - Molecular and cellular …, 2006 - Elsevier
Endometrial cancer is the most common malignancy of the female genital tract. Its incidence
correlates with prolonged estrogen stimulation unopposed by progesterone or synthetic …

The association between polycystic ovaries and endometrial cancer

OC Pillay, LFW Te Fong, JC Crow… - Human …, 2006 - academic.oup.com
BACKGROUND: Women with polycystic ovary syndrome (PCOS) are assumed to be at
increased risk of endometrial cancer (EC), albeit of a more differentiated type with better …

Prognostic impact of EMT (epithelial-mesenchymal-transition)-related protein expression in endometrial cancer

Y Tanaka, Y Terai, H Kawaguchi, S Fujiwara… - Cancer biology & …, 2013 - Taylor & Francis
Objectives: The epithelial-mesenchymal-transition (EMT) is an important step in the invasion
and metastasis of cancer. A critical molecular feature of this process is the downregulation of …

Abnormal expression of period 1 (PER1) in endometrial carcinoma

KT Yeh, MY Yang, TC Liu, JC Chen… - The Journal of …, 2005 - Wiley Online Library
The development of endometrial carcinoma (EC) is a multiple‐step process, which includes
inactivation of tumour suppressor genes, activation of oncogenes, and disturbance of cancer …