Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …

Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

The latest findings indicate the huge therapeutic potential of stem cells in regenerative
medicine, including the healing of chronic wounds. Main stem cell types involved in wound …

Human skin is a remarkable organ that sustains insult and injury throughout life. The ability
of skin to expeditiously repair wounds is paramount to survival. With an aging global …

Abstract Tissue-engineered skin (TES), as an analogue of native skin, is promising for
wound repair and regeneration. However, a major drawback of TES products is a lack of …

Significance: Almost 7 million Americans have chronic cutaneous wounds and billions of
dollars are spent on their treatment. The number of patients with nonhealing wounds keeps …

Background: Bone marrow aspirate concentrate (BMAC) has emerged as a therapeutic
option for symptomatic knee osteoarthritis (OA). Purpose: To systematically review the …

While wound therapy remains a clinical challenge in current medical practice, much effort
has focused on developing biological therapeutic approaches. This paper presents a …

Introduction The prevalence of nonhealing wounds is predicted to increase due to the
growing aging population. Despite the use of novel skin substitutes and wound dressings …

Worldwide, hard-to-heal lower limb wounds are estimated to affect 1.5–3% of the adult
population with a treatment-related annual cost of $10 billion. Thus, chronic skin ulcers of …