Introduction: Men are missing along the HIV care continuum. However, the estimated
proportions of men in sub-Saharan Africa meeting the UNAIDS 95-95-95 goals vary …

Background In 2016, we conducted a systematic review to assess the feasibility of treatment
monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in low …

Background Due to the high prevalence of resistance to NNRTI-based ART since 2018,
consolidated recommendations from the WHO have indicated dolutegravir as the preferred …

Background A barrier to HIV-1 cure rests in the persistence of proviral DNA in infected CD4+
leukocytes. The high HIV-1 mutation rate leads to viral diversity, immune evasion, and …

Point-of-care (POC) HIV viral load (VL) tests are needed to enhance access to HIV VL
testing in low-and middle-income countries (LMICs) and to enable HIV VL self-testing at …

Despite expanded antiretroviral therapy (ART) in South Africa, HIV-1 transmission persists.
Integrase strand transfer inhibitors (INSTI) and long-acting injectables offer potential for …

Importance Despite the widespread availability of antiretroviral therapy (ART), people with
HIV still experience high mortality after hospital admission. Objective To determine whether …

Background: Virologic failure in HIV predicts the development of drug resistance and
mortality. Genotypic resistance testing (GRT), which is the standard of care after virologic …

The retrovirus HIV-1 is the etiological agent of the decades-long AIDS pandemic. Although
vaccination is the most common preexposure route to prevent acquisition of viral disease …

The ability of HIV-1 to rapidly mutate leads to antiretroviral therapy (ART) failure among
infected patients. Drug-resistance mutations (DRMs), which cause a fitness penalty to …