[HTML][HTML] Identification of necroptosis-related subtypes, development of a novel signature, and characterization of immune infiltration in colorectal cancer

M Sun, X Ji, M Xie, X Chen, B Zhang, X Luo… - Frontiers in …, 2022 - frontiersin.org
Introduction Necroptosis, a type of programmed cell death, has recently been extensively
studied as an important pathway regulating tumor development, metastasis, and immunity …

[HTML][HTML] Engineering metal-organic framework nanoparticles trigger pyroptosis to boost colon cancer immunotherapy

X Wang, X Lu, X Yang, B Zhu, W Deng, Q Ye, B Bai… - Materials & Design, 2024 - Elsevier
Pyroptosis, which is a novel form of immunogenic cell death, plays a vital role in antitumor
therapy. Zirconium-based metal–organic frameworks (Zr-MOFs) have been applied in …

[HTML][HTML] Combination of immune checkpoint blockade and targeted gene regulation of angiogenesis for facilitating antitumor immunotherapy

J Zhan, M Zhang, L Zhou, C He - Frontiers in Bioengineering and …, 2023 - frontiersin.org
The rapid development of tumor immunotherapy has improved the management of patients
with cancer. However, several key problems of tumor immunotherapy, including the …

Differential profile of protumor immunological factors between the tumor site and the tumor-free site–predictive potential of IL-8 and COX2 for colorectal cancer and …

G Cui, A Yuan, Z Pang, J Florholmen - International Immunopharmacology, 2023 - Elsevier
To study the role of host immune surveillance in the initiation and progression of colorectal
cancer (CRC), a set of protumor immunological factors was determined by quantitative real …

[HTML][HTML] Somatic mutation profiling, tumor-infiltrating leukocytes, tertiary lymphoid structures and PD-L1 protein expression in HER2-amplified colorectal cancer

XT Liu, ZY Kou, H Zhang, J Dong, JH Zhang, YJ Peng… - PeerJ, 2023 - peerj.com
The status of human epidermal growth factor receptor 2 (HER2) for the prognosis in
colorectal cancer (CRC) is controversial, and the characteristics of the somatic mutation …

Longitudinal change of circulating tumor cell level and its relationship with immune checkpoint inhibitor-based treatment benefits in unresectable, metastatic colorectal …

H Fan, L Bai, K Bai - Scandinavian Journal of Clinical and …, 2023 - Taylor & Francis
Objective Circulating tumor cell (CTC) exerts diagnostic and prognostic value in colorectal
cancer (CRC) patients. This study intended to further investigate the longitudinal change of …

[PDF][PDF] Die Interaktion von T-Zellen und autologen kolorektalen Tumorzellen: Charakterisierung immunsuppressiver Mechanismen und Verbesserung der …

S Schwarz - 2022 - rosdok.uni-rostock.de
Ursächlich für das KRK sind meist gutartige Adenome, die aufgrund genetischer
Veränderungen entarten und in ein malignes Wachstum übergehen. Dieser als Adenom …

Pdgfrβ Participates in the Stat3-Mediated Regulation of Pd-L1 Expression in Colorectal Cancer

Y Zhou, FC Huang, D Ran, WR Lin, LH Zhu… - Available at SSRN … - papers.ssrn.com
Background: PD-L1 is related to colorectal cancer (CRC) prognosis; however, its role
remains unclear. The JAK2/STAT3 pathway regulates PD-L1 expression, and a negative …