Epithelial-mesenchymal transition (EMT) is involved in a variety of tissue fibroses.
Fibroblasts/myofibroblasts derived from epithelial cells contribute to the excessive …

Idiopathic pulmonary fibrosis (IPF) is a fatal disorder resulting from the progressive
remodeling of lungs, with no known effective treatment. Although transforming growth factor …

Pathologic features of idiopathic pulmonary fibrosis (IPF) include genetic predisposition,
activation of the unfolded protein response, telomere attrition, and cellular senescence. The …

Idiopathic pulmonary fibrosis (IPF) is a rare disease of the lung with a largely unknown
etiology and a poor prognosis. Intriguingly, forms of familial pulmonary fibrosis (FPF) have …

EMT and pathogenesis: the good, the bad and the ugly• TGF‐b—a central player in EMT•
Changes in cell–cell/cell–ECM adhesion in EMT—the role of integrins during EMT• TGF‐b …

MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …

Fibrosis is the leading cause of organ dysfunction in diseases such as systemic sclerosis,
liver cirrhosis, cardiac fibrosis, progressive kidney disease, and idiopathic pulmonary …

MicroRNAs are short noncoding RNA regulators that repress synthesis of their targets post‐
transcriptionally. On average, each microRNA is estimated to regulate several hundred …

Lung cancer is the most common cancer worldwide. Treatment options for lung cancer
include surgery, radiation therapy, chemotherapy, molecularly targeted therapy including …

Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Let-7 family has
been shown to function as a tumor suppressor through regulating multiple oncogenic …