Time is spine: a review of translational advances in spinal cord injury: JNSPG 75th Anniversary Invited Review Article

JH Badhiwala, CS Ahuja, MG Fehlings - Journal of Neurosurgery: Spine, 2018 - thejns.org
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical,
emotional, and economic consequences for patients, families, and society at large. Timely …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

3D printed stem‐cell derived neural progenitors generate spinal cord scaffolds

D Joung, V Truong, CC Neitzke, SZ Guo… - Advanced functional …, 2018 - Wiley Online Library
A bioengineered spinal cord is fabricated via extrusion‐based multimaterial 3D bioprinting,
in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor …

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Stem cell therapy for spinal cord injury

L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

A systematic review of cellular transplantation therapies for spinal cord injury

W Tetzlaff, EB Okon, S Karimi-Abdolrezaee… - Journal of …, 2011 - liebertpub.com
Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …

Repair of the injured spinal cord by transplantation of neural stem cells in a hyaluronan-based hydrogel

AJ Mothe, RY Tam, T Zahir, CH Tator, MS Shoichet - Biomaterials, 2013 - Elsevier
Traumatic injury to the spinal cord causes cell death, demyelination, axonal degeneration,
and cavitation resulting in functional motor and sensory loss. Stem cell therapy is a …

Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically …

S Karimi-Abdolrezaee, E Eftekharpour… - Journal of …, 2010 - Soc Neuroscience
The transplantation of neural stem/progenitor cells (NPCs) is a promising therapeutic
strategy for spinal cord injury (SCI). However, to date NPC transplantation has exhibited only …

Advances in stem cell therapy for spinal cord injury

AJ Mothe, CH Tator - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Spinal cord injury (SCI) is a devastating condition producing great personal and societal
costs and for which there is no effective treatment. Stem cell transplantation is a promising …

Clinical trials of stem cell treatment for spinal cord injury

K Yamazaki, M Kawabori, T Seki, K Houkin - International Journal of …, 2020 - mdpi.com
There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …