BACKGROUND Uterine natural killer cells (uNK) are the most abundant lymphocytes found
in the decidua during implantation and in first trimester pregnancy. They are important for …

Compared to most mammals, human pregnancy is unusual in that it involves chromosomally
diverse embryos, cyclical breakdown and regeneration of the uterine mucosa, and intimate …

• In this guideline, recurrent miscarriage has been defined as three or more first trimester
miscarriages. However, clinicians are encouraged to use their clinical discretion to …

Background Anticoagulant therapy might reduce the number of miscarriages and adverse
pregnancy outcomes in women with recurrent pregnancy loss and inherited thrombophilia …

Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

Objective To investigate whether a significant association between vitamin D status and the
risk of miscarriage or recurrent miscarriage (RM) exists. Design Systematic review and meta …

Rationale: Recurrent pregnancy loss (RPL) is a distressing disorder that seriously affects the
physical and psychological health of women. RPL is also a sentinel risk marker for future …

Recurrent spontaneous abortion (RSA) is defined as two or more pregnancy loss, affecting
the happiness index of fertility couples. The mechanisms involved in the occurrence of RSA …

Background Decidual macrophages participate in immune regulation at the maternal–fetal
interface. Abnormal M1/M2 polarization of decidual macrophages might predispose immune …

Research ethics considerations foreground minimising harm to participants. Whilst
increasing attention is being paid to researcher vulnerabilities, little has been written about …