Epidemiology of peripheral artery disease and polyvascular disease

AW Aday, K Matsushita - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic lower extremity peripheral artery disease (PAD) is increasingly recognized
as an important cause of cardiovascular morbidity and mortality that affects> 230 million …

Update on the pathophysiology and medical treatment of peripheral artery disease

J Golledge - Nature reviews cardiology, 2022 - nature.com
Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Advances in revascularization for peripheral artery disease: revascularization in PAD

JA Beckman, PA Schneider, MS Conte - Circulation research, 2021 - Am Heart Assoc
Effective revascularization of the patient with peripheral artery disease is about more than
the procedure. The approach to the patient with symptom-limiting intermittent claudication or …

Lower extremity peripheral artery disease without chronic limb-threatening ischemia: a review

TS Polonsky, MM McDermott - Jama, 2021 - jamanetwork.com
Importance Lower extremity peripheral artery disease (PAD) affects approximately 8.5
million people in the US and approximately 230 million worldwide. Observations Peripheral …

Canadian Cardiovascular Society 2022 guidelines for peripheral arterial disease

BL Abramson, M Al-Omran, SS Anand… - Canadian Journal of …, 2022 - Elsevier
Patients with widespread atherosclerosis such as peripheral artery disease (PAD) have a
high risk of cardiovascular and limb symptoms and complications, which affects their quality …

Contemporary medical management of peripheral artery disease

MP Bonaca, NM Hamburg, MA Creager - Circulation research, 2021 - Am Heart Assoc
Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. Modifiable
risk factors including cigarette smoking, dyslipidemia, diabetes, poor diet quality, obesity …

Antithrombotic agents: new directions in antithrombotic therapy

NC Chan, JI Weitz - Circulation research, 2019 - Am Heart Assoc
Recent advances in our understanding of the contribution of thrombin generation to arterial
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …

Atherosclerotic risk and statin use among patients with peripheral artery disease

LD Colantonio, D Hubbard, KL Monda, KE Mues… - Journal of the American …, 2020 - jacc.org
Background Peripheral artery disease (PAD) is associated with increased risk for
atherosclerotic cardiovascular disease (ASCVD) events. Objectives The goal of this study …

Polyvascular disease: reappraisal of the current clinical landscape

JA Gutierrez, AW Aday, MR Patel… - Circulation …, 2019 - Am Heart Assoc
Atherosclerosis within 2 or more arterial beds has been termed polyvascular disease.
Although polyvascular disease has long been associated with heightened cardiovascular …

High TG to HDL ratio plays a significant role on atherosclerosis extension in prediabetes and newly diagnosed type 2 diabetes subjects

R Scicali, P Giral, L d'Erasmo, P Cluzel… - Diabetes/metabolism …, 2021 - Wiley Online Library
Aims We investigated the role of TG to HDL ratio (TG/HDL) on atherosclerosis extension,
defined as presence of coronary artery calcium (CAC), carotid and femoral plaque, in …