MSC-EVs alleviate osteoarthritis by regulating microenvironmental cells in the articular cavity and maintaining cartilage matrix homeostasis
B You, C Zhou, Y Yang - Ageing research reviews, 2023 - Elsevier
Osteoarthritis (OA), a common cause of chronic articular cartilage degeneration, is the main
cause of disability in older adults and severely affects quality of life. Multiple factors are …
cause of disability in older adults and severely affects quality of life. Multiple factors are …
Intraarticular injections of mesenchymal stem cells in knee osteoarthritis: a review of their current molecular mechanisms of action and their efficacy
EC Rodríguez-Merchán - International Journal of Molecular Sciences, 2022 - mdpi.com
More than 10% of the world's population suffers from osteoarthritis (OA) of the knee, with a
lifetime risk of 45%. Current treatments for knee OA pain are as follows: weight control; oral …
lifetime risk of 45%. Current treatments for knee OA pain are as follows: weight control; oral …
Advances in Stem Cell-Based Therapies in the Treatment of Osteoarthritis
Y Chen, RJ Cheng, Y Wu, D Huang, Y Li… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic, degenerative joint disease presenting a significant global
health threat. While current therapeutic approaches primarily target symptom relief, their …
health threat. While current therapeutic approaches primarily target symptom relief, their …
Decellularized allogeneic cartilage paste with human costal cartilage and crosslinked hyaluronic acid-carboxymethyl cellulose carrier augments microfracture for …
Articular cartilage lacks natural healing abilities and necessitates surgical treatments for
injuries. While microfracture (MF) is a primary surgical approach, it often results in the …
injuries. While microfracture (MF) is a primary surgical approach, it often results in the …
Immunoregulatory paracrine effect of mesenchymal stem cells and mechanism in the treatment of osteoarthritis
X Zhang, T Liu, C Ran, W Wang, F Piao… - Frontiers in Cell and …, 2024 - frontiersin.org
Osteoarthritis (OA) is a degenerative joint disease caused by chronic inflammation that
damages articular cartilage. At present, the treatment of OA includes drug therapy to relieve …
damages articular cartilage. At present, the treatment of OA includes drug therapy to relieve …
[HTML][HTML] Ameliorative effects of undifferentiated and differentiated BM-MSCs in MIA-induced osteoarthritic Wistar rats: roles of NF-κB and MMPs signaling pathways
AS Saleh, M Abdel-Gabbar, H Gabr… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objectives: Osteoarthritis (OA) is a degenerative joint condition that is persistent. OA affects
millions of people throughout the world. Both people and society are heavily economically …
millions of people throughout the world. Both people and society are heavily economically …
Two Amnion-Derived Mesenchymal Stem-Cells Injections to Osteoarthritic Elbows in Dogs—Pilot Study
M Domaniza, M Hluchy, D Cizkova, F Humenik… - Animals, 2023 - mdpi.com
Simple Summary Osteoarthritis is a degenerative disease of synovial joints characterized by
joint inflammation, damage of articular cartilage, and degenerative changes in periarticular …
joint inflammation, damage of articular cartilage, and degenerative changes in periarticular …
Osteoarthritis induced by monosodium iodoacetate model: evolution of inflammatory, nociceptive and histopathological markers
FG da Silva Nascimento… - Journal of Health …, 2024 - unichristus.emnuvens.com.br
Objectives: this study aimed to highlight the evolution of the osteoarthritis (OA) model
induced by monosodium iodoacetate (MIA) and its collaboration with the knowledge of the …
induced by monosodium iodoacetate (MIA) and its collaboration with the knowledge of the …
Ameliorative Effects of Bone Marrow-derived Mesenchymal Stem Cells and Hyaluronic Acid on Monosodium Iodoacetate-Induced Ankle Osteoarthritis in Wistar Rats …
U Hagag, FM Halfaya, HM Al-Muzafar, SS Al-Jameel… - 2023 - researchsquare.com
Background: There is currently no cure for osteoarthritis [OA], and the few pharmacological
therapy options available have drawbacks. Additionally, there is no effective treatment that …
therapy options available have drawbacks. Additionally, there is no effective treatment that …