All metazoans that utilize molecular oxygen (O2) for metabolic purposes have the capacity to
adapt to hypoxia, the condition that arises when O2 demand exceeds supply. This is …

Molecular oxygen (O2) and carbon dioxide (CO2) are the primary gaseous substrate and
product of oxidative phosphorylation in respiring organisms, respectively. Variance in the …

There is no consensus on the optimal pCO2 levels in the newborn. We reviewed the effects
of hypercapnia and hypocapnia and existing carbon dioxide thresholds in neonates. A …

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The
IPF-conditioned matrix (IPF-CM) system enables the study of matrix–fibroblast interplay …

Mismatch between CO 2 production (Vco 2) and respiration underlies the pathogenesis of
obesity hypoventilation. Leptin-mediated CNS pathways stimulate both metabolism and …

Carbon dioxide (CO2) is a fundamental physiological gas known to profoundly influence the
behaviour and health of millions of species within the plant and animal kingdoms in …

CO 2 is a physiological gas normally produced in the body during aerobic respiration.
Hypercapnia (elevated blood pCO 2>≈ 50 mm Hg) is a feature of several lung pathologies …

The intestinal mucosa is exposed to fluctuations in oxygen levels due to constantly changing
rates of oxygen demand and supply and its juxtaposition with the anoxic environment of the …

This review summarizes sleep deprivation, breathing regulation during sleep, and the
outcomes of its destabilization. Breathing as an automatically regulated task consists of …

New Findings What is the central question of this study? Microglia are presumed to be the
source of inflammatory mediators that contribute to hypoxia‐induced neuroinflammation …