Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …

Alzheimer's disease (AD) is a common neurodegenerative disease, mainly manifested by
cognitive dysfunction. It seriously reduces the quality of life, and there is no ideal treatment …

Aluminium is a metal known to cause neurotoxicity in the brain, by promoting
neurodegeneration and affecting memory and cognitive ability. AlCl 3 has been reported to …

Tetrahydrobipterin (BH4) is a pivotal enzymatic cofactor required for the synthesis of
serotonin, dopamine and nitric oxide. BH4 is essential for numerous physiological …

Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

Increase of deposits of amyloid β peptides in the extracellular matrix is landmark during
Alzheimer's Disease (AD) due to the imbalance in the production vs. clearance. This …

The aim of the present study was to investigate the expression levels of microRNA (miR)‑
4722‑5p and miR‑615‑3p in Alzheimer's disease (AD) and their diagnostic value. Blood …

There is an ongoing debate about the value of animal research in psychiatry with valid lines
of reasoning stating the limits of individual animal models compared to human psychiatric …

Background Although numerous microRNAs (miRNAs) have been discovered to participate
in the progression of Alzheimer's disease (AD), they are still difficult to apply in clinical work …

MicroRNAs (miRs) are small non-coding pieces of RNA that are involved in a variety of
physiologic processes such as apoptosis, cell proliferation, cell differentiation, cell cycle and …