[HTML][HTML] Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

KR Lee, K Kim, J Jung, JH Heo, S Cho, S Lee… - Sensors, 2013 - mdpi.com
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …

[HTML][HTML] Advances in the measurement of red blood cell deformability: A brief review

J Kim, HY Lee, S Shin - Journal of Cellular Biotechnology, 2015 - content.iospress.com
Red blood cells (RBCs) exhibit a unique deformability, which enables them to change shape
reversibly in response to an external force. The deformability of RBCs allows them to flow in …

Theory and algorithms to compute Helfrich bending forces: a review

A Guckenberger, S Gekle - Journal of Physics: Condensed …, 2017 - iopscience.iop.org
Cell membranes are vital to shield a cell's interior from the environment. At the same time
they determine to a large extent the cell's mechanical resistance to external forces. In recent …

[HTML][HTML] Profiling individual human red blood cells using common-path diffraction optical tomography

Y Kim, H Shim, K Kim, HJ Park, S Jang, YK Park - Scientific reports, 2014 - nature.com
Due to its strong correlation with the pathophysiology of many diseases, information about
human red blood cells (RBCs) has a crucial function in hematology. Therefore, measuring …

Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases

E Pretorius, DB Kell - Integrative biology, 2014 - academic.oup.com
Most non-communicable diseases involve inflammatory changes in one or more vascular
systems, and there is considerable evidence that unliganded iron plays major roles in this …

[HTML][HTML] Deformation of red blood cells, air bubbles, and droplets in microfluidic devices: Flow visualizations and measurements

D Bento, RO Rodrigues, V Faustino, D Pinho… - Micromachines, 2018 - mdpi.com
Techniques, such as micropipette aspiration and optical tweezers, are widely used to
measure cell mechanical properties, but are generally labor-intensive and time-consuming …

[HTML][HTML] Stiffness increase of red blood cells during storage

Z Xu, Y Zheng, X Wang, N Shehata, C Wang… - Microsystems & …, 2018 - nature.com
In transfusion medicine, the deformability of stored red blood cells (RBCs) changes during
storage in blood banks. Compromised RBC deformability can reduce the transfusion …

Learning-based screening of hematologic disorders using quantitative phase imaging of individual red blood cells

G Kim, YJ Jo, H Cho, H Min, YK Park - Biosensors and Bioelectronics, 2019 - Elsevier
We present a rapid and label-free method for hematologic screening for diseases and
syndromes, utilizing quantitative phase imaging (QPI) and machine learning. We aim to …

Erythrocytes and their role as health indicator: Using structure in a patient-orientated precision medicine approach

E Pretorius, O Oore-ofe, S Mbotwe, J Bester - Blood reviews, 2016 - Elsevier
The relevance of erythrocyte light microscopy analysis (a well-known haematological
method) is under the spotlight, however there is a place for innovative electron …

Common-path diffraction optical tomography for investigation of three-dimensional structures and dynamics of biological cells

Y Kim, H Shim, K Kim, HJ Park, JH Heo, J Yoon… - Optics express, 2014 - opg.optica.org
We present an optical holographic micro-tomographic technique for imaging both the three-
dimensional structures and dynamics of biological cells. Optical light field images of a …