Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital
participant in primary cellular functions, such as proliferation, survival, migration, and …

Simple Summary Prostate cancer (PCa) is the second most frequent type of cancer in men
worldwide. Treatment options for early-stage PCa include external beam radiation therapy …

Simple Summary The present study investigated the anticancer effects and molecular
mechanisms of apigenin in cervical cancer in vitro and in vivo. HeLa and C33A cells were …

The revolution in cancer immunotherapy over the last few decades has resulted in a
paradigm shift in the clinical care of cancer. Most of the cancer immunotherapeutic regimens …

The application of immune checkpoint inhibitors and FGFR protein tyrosine kinase inhibitors
have made a tremendous breakthrough in bladder cancer therapy. However, inadequate …

Activation of the Wnt pathway lies at the core of many human cancers. Wnt and
macropinocytosis are often active in the same processes, and understanding how Wnt …

Epigenetic regulation and Focal adhesion kinase (FAK) are considered to be two important
targets for the development of antitumor drugs. Studies have shown that the combination of …

Part of the broader glycosphingolipid family, gangliosides are composed of a ceramide
bound to a sialic acid-containing glycan chain, and locate at the plasma membrane …

Simple Summary Breast cancer that has metastasized to other parts of the body still has a
high incidence and mortality rate. Furthermore, treating metastatic breast cancer remains a …

Breast cancer (BC) involves complex signaling networks characterized by extensive cross-
communication and feedback loops between and within multiple signaling cascades. Many …