肿瘤的发生机制复杂, 而肿瘤的播散更是一个多方面参与的过程, 其中细胞骨架的失调及细胞外
基质的破坏, 上皮间质转化(Epithelial-mesenchymal transition, EMT) 扮演的角色至关重要 …

Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences,
wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article …

Quantitative comparison of ligand-target interaction profiles is often challenging due to
subjective interpretations in visual inspection or limitation to predefined interactions in …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase overexpressed in various
cancer types that plays a critical role in tumor progression. Accumulating evidence suggests …

Background The research of cancer treatments has always been a hot topic in medical field.
Cancer monotherapy as a common therapy has been proven to have many disadvantages …

Alterations in cellular calcium (Ca2+) signals have been causally associated with the
development and progression of human cancers. Cellular Ca2+ signals are generated by …

Breast cancer (BC) incidence increases with age, and a substantial proportion of aggressive
forms of BC are observed in older women. The mechanisms underlying BC's age …

The revolution in cancer immunotherapy over the last few decades has resulted in a
paradigm shift in the clinical care of cancer. Most of the cancer immunotherapeutic regimens …

Due to the complexity of cancer treatment, there is a need to embrace more advanced
approaches in cancer therapy. Targeted therapies are cancer treatment that targets proteins …