Comparative studies on brain asymmetry date back to the 19th century but then largely
disappeared due to the assumption that lateralization is uniquely human. Since the …

Five years into thesmall RNA revolution'it is hard not to share in the excitement about the
rapidly unravelling biology of microRNAs. Since the discovery of the first microRNA gene, lin …

To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile
the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial …

Left-right asymmetries in brains are usually minor or cryptic. We report brain asymmetries in
the tiny, dorsal tubular nervous system of the ascidian tadpole larva, Ciona intestinalis …

The~ 100 MB genome of C. elegans codes for~ 20,000 protein-coding genes many of which
are required for the function of the nervous system, composed of 302 neurons in the adult …

The brains of humans and other animals are asymmetrically organized, but we still know
little about the ontogenetic and neural fundaments of lateralizations. Here, we review the …

Understanding the principles of information processing in neural circuits requires systematic
characterization of the participating cell types and their connections, and the ability to …

The strong predominance of right-handedness appears to be a uniquely human
characteristic, whereas the left-cerebral dominance for vocalization occurs in many species …

How left/right functional asymmetry is layered on top of an anatomically symmetrical nervous
system is poorly understood. In the nematode Caenorhabditis elegans, two morphologically …

Evidence of left–right asymmetries in invertebrates has begun to emerge, suggesting that
lateralization of the nervous system may be a feature of simpler brains as well as more …