LncRNAs in ovarian cancer progression, metastasis, and main pathways: ceRNA and alternative mechanisms

EA Braga, MV Fridman, AA Moscovtsev… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …

The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers

J Wang, L Chen, P Qiang - Cancer cell international, 2021 - Springer
The human insulin-like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2/IMP2) is
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

EN Kotnik, MM Mullen, NC Spies, T Li… - Communications …, 2023 - nature.com
High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and
the majority of cases present with metastasis and late-stage disease. Over the last few …

Wet chemical mediated hematite α-Fe2O3 nanoparticles synthesis: preparation, characterization and anticancer activity against human metastatic ovarian cancer

V Ramalingam, M Harshavardhan, SD Kumar - Journal of Alloys and …, 2020 - Elsevier
Ovarian cancer (OC) is the most common gynecologic cancer incidence in female and the
surgery in the major treatment option for OC which makes difficult for survival of OC patients …

Aptamers as potential therapeutic tools for ovarian cancer: Advancements and challenges

W Szymanowski, A Szymanowska, A Bielawska… - Cancers, 2023 - mdpi.com
Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

Long noncoding RNA WDFY3‐AS2 suppresses tumor progression by acting as a competing endogenous RNA of microRNA‐18a in ovarian cancer

W Li, S Ma, X Bai, W Pan, L Ai… - Journal of cellular …, 2020 - Wiley Online Library
Ovarian cancer (OC) is a fatal cancer in women, mainly due to its aggressive nature and
poor survival rate. The lncRNA‐miRNA‐mRNA (long noncoding RNA‐microRNA …

Comprehensive analyses of glycolysis-related lncRNAs for ovarian cancer patients

J Zheng, J Guo, L Zhu, Y Zhou, J Tong - Journal of ovarian research, 2021 - Springer
Background Not only glycolysis but also lncRNAs play a significant role in the growth,
proliferation, invasion and metastasis of of ovarian cancer (OC). However, researches about …

LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis

Y Wu, T Wang, L Xia, M Zhang - Cancer Cell International, 2021 - Springer
Background Ovarian cancer (OC) is a high-mortality gynecological cancer that is typically
treated with cisplatin, although such treatment often results in chemoresistance. Ovarian …

NEAT1 knockdown suppresses the cisplatin resistance in ovarian cancer by regulating miR-770-5p/PARP1 axis

M Zhu, L Yang, X Wang - Cancer management and research, 2020 - Taylor & Francis
Background Long noncoding RNAs play essential roles in regulating drug resistance in
cancers. However, how and whether lncRNA nuclear paraspeckle assembly transcript 1 …

Efficacy evaluation of multi-immunotherapy in ovarian cancer: from bench to bed

X Hu, C Bian, X Zhao, T Yi - Frontiers in immunology, 2022 - frontiersin.org
Ovarian cancer, one of the most common gynecological malignancies, is characterized by
high mortality and poor prognosis. Cytoreductive surgery and chemotherapy remain the …