[HTML][HTML] Translating the immune microenvironment of thyroid cancer into clinical practice

LL Cunha, LS Ward - Endocrine-Related Cancer, 2022 - erc.bioscientifica.com
Thyroid cancer is an excellent model for studying tumor immune microenvironment, as it
often shows local signs of an immune response. The tumor immune microenvironment of …

[HTML][HTML] Dynamic cancer cell heterogeneity: diagnostic and therapeutic implications

V Jacquemin, M Antoine, G Dom, V Detours… - Cancers, 2022 - mdpi.com
Simple Summary Cancer heterogeneity, which occurs in most cancer patients, has been
known and studied by experienced pathologists since the early 19th century. Intratumoral …

[HTML][HTML] The immune landscape of papillary thyroid cancer in the context of autoimmune thyroiditis

F Pani, P Caria, Y Yasuda, M Makoto, S Mariotti… - Cancers, 2022 - mdpi.com
Simple Summary The association between papillary thyroid cancer and Hashimoto's
thyroiditis went through a long-standing human debate recently elucidated by the …

[HTML][HTML] The tumor microenvironment and the estrogen loop in thyroid cancer

N Denaro, R Romanò, S Alfieri, A Dolci, L Licitra… - Cancers, 2023 - mdpi.com
Simple Summary The composite network of stromal, immune, vascular and cancer cells,
which constitutes the tumor microenvironment (TME), has emerged as a player in thyroid …

TREM1 fosters an immunosuppressive tumor microenvironment in papillary thyroid cancer

Y Zhao, C Zhang, Y Zhu, X Ding… - Endocrine-Related …, 2022 - erc.bioscientifica.com
The immunosuppressive microenvironment is associated with poor prognosis in papillary
thyroid cancer (PTC); however, the molecular mechanisms involved are unknown. Among …

Upregulation of dendrocyte-expressed seven transmembrane protein is associated with unfavorable outcomes in differentiated thyroid cancer

JJ Lee, YC Hsu, WC Huang, SP Cheng - Endocrine, 2023 - Springer
Purpose Dendritic cell infiltrates are increased in thyroid cancer but may have a defective
ability to provoke effective immune responses. In this study, we aimed to identify potential …

[HTML][HTML] Roles and new insights of macrophages in the tumor microenvironment of thyroid cancer

Q Liu, W Sun, H Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
Although most thyroid cancers have a good and predictable prognosis, the anaplastic,
medullary, and refractory thyroid cancers still prone to recurrence and metastasis, resulting …

[HTML][HTML] Integration of scRNA and bulk RNA-sequence to construct the 5-gene molecular prognostic model based on the heterogeneity of thyroid carcinoma …

Z Ni, S Cong, H Li, J Liu, Q Zhang, C Wei… - Acta Biochimica et …, 2024 - ncbi.nlm.nih.gov
Thyroid cancer (TC) is a kind of cancer with high heterogeneity, which leads to significant
difference in prognosis. The prognostic molecular processes are not well understood …

[HTML][HTML] Extra-cellular vesicles derived from thyroid cancer cells promote the epithelial to mesenchymal transition (EMT) and the transfer of malignant phenotypes …

S Mardente, M Aventaggiato, E Splendiani… - International Journal of …, 2023 - mdpi.com
Thyroid cancer is the most common endocrine cancer, and its incidence is increasing in
many countries around the world. Among thyroid cancers, the papillary thyroid cancer (PTC) …

[HTML][HTML] Integrated analysis of fibroblasts molecular features in papillary thyroid cancer combining single-cell and bulk RNA sequencing technology

W Li, Z Liu, X Cen, J Xu, S Zhao, B Wang… - Frontiers in …, 2022 - frontiersin.org
Background Papillary thyroid cancer (PTC) is the most common pathological type of thyroid
cancer with a high incidence globally. Increasing evidence reported that fibroblasts …