[HTML][HTML] Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes

N Marx, M Husain, M Lehrke, S Verma, N Sattar - Circulation, 2022 - Am Heart Assoc
Patients with type 2 diabetes are at high risk for development of cardiovascular disease,
including myocardial infarction, stroke, heart failure, and cardiovascular death. Multiple large …

[HTML][HTML] Type II diabetes mellitus: a review on recent drug based therapeutics

S Padhi, AK Nayak, A Behera - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …

[HTML][HTML] Weight loss and maintenance related to the mechanism of action of glucagon-like peptide 1 receptor agonists

J Ard, A Fitch, S Fruh, L Herman - Advances in therapy, 2021 - Springer
Obesity is a chronic disease associated with many complications. Weight loss of 5–15% can
improve many obesity-related complications. Despite the benefits of weight reduction, there …

[HTML][HTML] Inflammation and oxidative stress in diabetic kidney disease: the targets for SGLT2 inhibitors and GLP-1 receptor agonists

A Winiarska, M Knysak, K Nabrdalik… - International Journal of …, 2021 - mdpi.com
The incidence of type 2 diabetes (T2D) has been increasing worldwide, and diabetic kidney
disease (DKD) remains one of the leading long-term complications of T2D. Several lines of …

Tirzepatide for the treatment of adults with type 2 diabetes: an endocrine perspective

C De Block, C Bailey, C Wysham… - Diabetes, Obesity …, 2023 - Wiley Online Library
Tirzepatide is a novel glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide
1 (GLP‐1) receptor agonist approved in the United States as an adjunct to diet and exercise …

[HTML][HTML] Recent updates on GLP-1 agonists: Current advancements & challenges

D Sharma, S Verma, S Vaidya, K Kalia… - Biomedicine & …, 2018 - Elsevier
Abstract Glucagon-like peptide (GLP)-1 is an incretin hormone exhibiting several
pharmacological actions such as neuroprotection, increased cognitive function, cardio …

[HTML][HTML] In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes

J Riyaphan, DC Pham, MK Leong, CF Weng - Biomolecules, 2021 - mdpi.com
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors,
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …

Chronotherapy for hypertension

NP Bowles, SS Thosar, MX Herzig, SA Shea - Current hypertension …, 2018 - Springer
Abstract Purpose of Review Given the emerging knowledge that circadian rhythmicity exists
in every cell and all organ systems, there is increasing interest in the possible benefits of …

Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases

S Khemka, A Reddy, RI Garcia, M Jacobs… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. Genetic mutations cause a small …