[HTML][HTML] Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems
TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …
socioeconomic consequences. Although the underlying reasons are generally understood …
GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes
Patients with type 2 diabetes are at high risk for development of cardiovascular disease,
including myocardial infarction, stroke, heart failure, and cardiovascular death. Multiple large …
including myocardial infarction, stroke, heart failure, and cardiovascular death. Multiple large …
[HTML][HTML] Type II diabetes mellitus: a review on recent drug based therapeutics
S Padhi, AK Nayak, A Behera - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …
[HTML][HTML] Weight loss and maintenance related to the mechanism of action of glucagon-like peptide 1 receptor agonists
J Ard, A Fitch, S Fruh, L Herman - Advances in therapy, 2021 - Springer
Obesity is a chronic disease associated with many complications. Weight loss of 5–15% can
improve many obesity-related complications. Despite the benefits of weight reduction, there …
improve many obesity-related complications. Despite the benefits of weight reduction, there …
[HTML][HTML] Inflammation and oxidative stress in diabetic kidney disease: the targets for SGLT2 inhibitors and GLP-1 receptor agonists
A Winiarska, M Knysak, K Nabrdalik… - International Journal of …, 2021 - mdpi.com
The incidence of type 2 diabetes (T2D) has been increasing worldwide, and diabetic kidney
disease (DKD) remains one of the leading long-term complications of T2D. Several lines of …
disease (DKD) remains one of the leading long-term complications of T2D. Several lines of …
Tirzepatide for the treatment of adults with type 2 diabetes: an endocrine perspective
C De Block, C Bailey, C Wysham… - Diabetes, Obesity …, 2023 - Wiley Online Library
Tirzepatide is a novel glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide
1 (GLP‐1) receptor agonist approved in the United States as an adjunct to diet and exercise …
1 (GLP‐1) receptor agonist approved in the United States as an adjunct to diet and exercise …
[HTML][HTML] Recent updates on GLP-1 agonists: Current advancements & challenges
D Sharma, S Verma, S Vaidya, K Kalia… - Biomedicine & …, 2018 - Elsevier
Abstract Glucagon-like peptide (GLP)-1 is an incretin hormone exhibiting several
pharmacological actions such as neuroprotection, increased cognitive function, cardio …
pharmacological actions such as neuroprotection, increased cognitive function, cardio …
[HTML][HTML] In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors,
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …
Chronotherapy for hypertension
Abstract Purpose of Review Given the emerging knowledge that circadian rhythmicity exists
in every cell and all organ systems, there is increasing interest in the possible benefits of …
in every cell and all organ systems, there is increasing interest in the possible benefits of …
Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases
S Khemka, A Reddy, RI Garcia, M Jacobs… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. Genetic mutations cause a small …
memory loss and multiple cognitive impairments. Genetic mutations cause a small …