Short-chain fatty acids-producing probiotics: A novel source of psychobiotics

Y Cheng, J Liu, Z Ling - Critical Reviews in Food Science and …, 2022 - Taylor & Francis
Psychobiotics—live microorganisms with potential mental health benefits, which can
modulate the microbiota-gut-brain-axis via immune, humoral, neural, and metabolic …

[HTML][HTML] Postsynaptic Proteins at Excitatory Synapses in the Brain—Relationship with Depressive Disorders

S Samojedny, E Czechowska… - International journal of …, 2022 - mdpi.com
Depressive disorders (DDs) are an increasingly common health problem that affects all age
groups. DDs pathogenesis is multifactorial. However, it was proven that stress is one of the …

[HTML][HTML] Role of Ca2+/calmodulin-dependent protein kinase type II in mediating function and dysfunction at glutamatergic synapses

AG Mohanan, S Gunasekaran, RS Jacob… - Frontiers in molecular …, 2022 - frontiersin.org
Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …

Understanding the pathogenetic mechanisms underlying altered neuronal function associated with CAMK2B mutations

R Borghi, M Trivisano, N Specchio, M Tartaglia… - Neuroscience & …, 2023 - Elsevier
Abstract 'Dominant mutations in CAMK2B, encoding a subunit of the calcium/calmodulin-
dependent protein kinase II (CAMK2), a serine/threonine kinase playing a key role in …

[HTML][HTML] Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation

AT Olson, Y Kang, AM Ladha, S Zhu, CB Lim… - PLoS …, 2023 - journals.plos.org
Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases
including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with …

Role of CAMK2D in neurodevelopment and associated conditions

PMF Rigter, C de Konink, MJ Dunn, MP Onori… - The American Journal of …, 2024 - cell.com
The calcium/calmodulin-dependent protein kinase type 2 (CAMK2) family consists of four
different isozymes, encoded by four different genes—CAMK2A, CAMK2B, CAMK2G, and …

[HTML][HTML] Loss of CAMK2G affects intrinsic and motor behavior but has minimal impact on cognitive behavior

PMF Rigter, C de Konink… - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction The gamma subunit of calcium/calmodulin-dependent protein kinase 2
(CAMK2G) is expressed throughout the brain and is associated with neurodevelopmental …

LPC20K modified from krill oil ameliorates the scopolamine-induced cognitive impairment

K Park, CH Kong, WC Kang, M Jeon, WH Lee… - Behavioural Brain …, 2024 - Elsevier
Alzheimer's disease (AD) is characterized by cognitive impairment. It is common in the
elderly. Etiologically, dysfunction of cholinergic neurotransmitter system is prominent in AD …

[HTML][HTML] Förster resonance energy transfer-based kinase mutation phenotyping reveals an aberrant facilitation of Ca2+/calmodulin-dependent CaMKIIα activity in de …

H Fujii, H Kidokoro, Y Kondo, M Kawaguchi… - Frontiers in Molecular …, 2022 - frontiersin.org
CaMKIIα plays a fundamental role in learning and memory and is a key determinant of
synaptic plasticity. Its kinase activity is regulated by the binding of Ca2+/CaM and by …

Insulin-like growth factor-1 promotes synaptogenesis signaling, a major dysregulated pathway in malformation of cortical development, in a rat model

M Lee, EJ Kim, MJ Kim, MS Yum, J Yeom, K Kim - Molecular Neurobiology, 2023 - Springer
Malformation of cortical development (MCD) is one of the main causes of intractable
epilepsy in childhood. We explored a treatment based on molecular changes using an infant …