During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions
that are supported by the neocortex. The neocortex, which forms almost 80% of the human …

Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

Markers of inhibitory neurotransmission are altered in the prefrontal cortex (PFC) of subjects
with schizophrenia, and several lines of evidence suggest that these alterations may be …

The analysis of microcircuitry (the connectivity at the level of individual neuronal processes
and synapses), which is indispensable for our understanding of brain function, is based on …

Here we describe mechanisms regulating area patterning of developing mammalian
neocortex, referred to as arealization. Current findings indicate an interplay between intrinsic …

Cerebral cortical functions are conducted by two general classes of neurons: glutamatergic
projection neurons and GABAergic interneurons. Distinct interneuron subtypes serve distinct …

It remains to be clarified how many classes of GABAergic nonpyramidal cells exist in the
cortical circuit. We have divided GABA cells in the rat frontal cortex into 3 groups, based on …

Anatomical, electrophysiological and molecular diversity of basket cell-like interneurons in
layers II–IV of rat somatosensory cortex were studied using patch-clamp electrodes filled …