[HTML][HTML] The miRNA–target interactions: An underestimated intricacy

C Diener, A Keller, E Meese - Nucleic Acids Research, 2024 - academic.oup.com
MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …

g: Profiler—interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)

L Kolberg, U Raudvere, I Kuzmin, P Adler… - Nucleic acids …, 2023 - academic.oup.com
Abstract g: Profiler is a reliable and up-to-date functional enrichment analysis tool that
supports various evidence types, identifier types and organisms. The toolset integrates many …

The FOXO family of transcription factors: key molecular players in gastric cancer

Y Liu, X Ao, Y Jia, X Li, Y Wang, J Wang - Journal of Molecular Medicine, 2022 - Springer
Gastric cancer (GC) is the fifth most frequently diagnosed cancer worldwide and the third
leading cause of cancer-related death with an oncological origin. Despite its decline in …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

DIANA-miRPath v4. 0: expanding target-based miRNA functional analysis in cell-type and tissue contexts

S Tastsoglou, G Skoufos, M Miliotis… - Nucleic Acids …, 2023 - academic.oup.com
DIANA-miRPath is an online miRNA analysis platform harnessing predicted or
experimentally supported miRNA interactions towards the exploration of combined miRNA …

Variational gated autoencoder-based feature extraction model for inferring disease-miRNA associations based on multiview features

Y Guo, D Zhou, X Ruan, J Cao - Neural Networks, 2023 - Elsevier
MicroRNAs (miRNA) play critical roles in diverse biological processes of diseases. Inferring
potential disease-miRNA associations enable us to better understand the development and …

[HTML][HTML] Transcriptional linkage analysis with in vivo AAV-Perturb-seq

AJ Santinha, E Klingler, M Kuhn, R Farouni, S Lagler… - Nature, 2023 - nature.com
The ever-growing compendium of genetic variants associated with human pathologies
demands new methods to study genotype–phenotype relationships in complex tissues in a …

TarBase-v9. 0 extends experimentally supported miRNA–gene interactions to cell-types and virally encoded miRNAs

G Skoufos, P Kakoulidis, S Tastsoglou… - Nucleic Acids …, 2024 - academic.oup.com
TarBase is a reference database dedicated to produce, curate and deliver high quality
experimentally-supported microRNA (miRNA) targets on protein-coding transcripts. In its …

Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice

I Cimen, L Natarelli, Z Abedi Kichi… - Science translational …, 2023 - science.org
The CXC chemokine receptor 4 (CXCR4) in endothelial cells (ECs) and vascular smooth
muscle cells (VSMCs) is crucial for vascular integrity. The atheroprotective functions of …

DIANA-microT 2023: including predicted targets of virally encoded miRNAs

S Tastsoglou, A Alexiou, D Karagkouni… - Nucleic acids …, 2023 - academic.oup.com
DIANA-microT-CDS is a state-of-the-art miRNA target prediction algorithm catering the
scientific community since 2009. It is one of the first algorithms to predict miRNA binding …