Routine use of diuretics and neurohumoral activation make hypokalemia (serum K+< 3. 5
mM) a prevalent electrolyte disorder among heart failure patients, contributing to the …

Cellular therapy for cardiovascular disease heralds an exciting frontier of research.
Mesenchymal stromal cells (MSCs) are present in adult tissues, including bone marrow and …

Patients with heart failure continue to suffer adverse health consequences despite advances
in therapies over the past 2 decades. Identification of novel therapeutic targets that may …

A wealth of investigations, ranging from clinical and animal model studies to in vitro
analyses, have generated great interest in the cardiovascular effects of leptin. Accordingly …

During post-natal maturation of the mammalian heart, proliferation of cardiomyocytes
essentially ceases as cardiomyocytes withdraw from the cell cycle and develop blocks at the …

Background: To investigate the cardiotoxic role of reactive oxygen species (ROS) and of
products derived from catecholamines auto‐oxidation, we studied:(1) the response of …

Efforts in modeling cardiovascular and respiratory control have been ongoing for a number
of years. These efforts include seminal work by AC Guyton and coworkers and F. Grodins …

Abstract Context Traditional Chinese medicine plays an important role in the prevention and
treatment of heart failure (HF). Linggui Zhugan decoction has been approved for clinical …

Background Tissue fibrosis and chamber remodeling is a hallmark of the failing heart and
the final common pathway for heart failure of diverse etiologies. Sustained elevation of pro …

Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …