Physicochemical aspects of the tumour microenvironment as drivers of vasculogenic mimicry

E Andreucci, S Peppicelli, J Ruzzolini… - Cancer and Metastasis …, 2022 - Springer
Tumour vascularisation is vital for cancer sustainment representing not only the main source
of nutrients and oxygen supply but also an escape route for single or clustered cancer cells …

Therapeutic potential of vasculogenic mimicry in urological tumors

X Lin, S Long, C Yan, X Zou, G Zhang, J Zou… - Frontiers in …, 2023 - frontiersin.org
Angiogenesis is an essential process in the growth and metastasis of cancer cells, which
can be hampered by an anti-angiogenesis mechanism, thereby delaying the progression of …

Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma

M Chmielewska-Kassassir, K Sobierajska… - Cancers, 2023 - mdpi.com
Simple Summary Malignant pleural mesothelioma belongs to the aggressive tumor of pleura
commonly recognized at the advanced, chemoresistant stage. Thymidylate synthase (TYMS) …

The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis

R Zhang, D Zhang, F Han, X Song, Y Zhang… - Journal of Experimental …, 2024 - Springer
Rhabdomyosarcoma (RMS) is a rare malignancy and the most common soft tissue sarcoma
in children. Vasculogenic mimicry (VM) is a novel tumor microcirculation model different from …

Iron deficiency increases phosphorylation of SP1 to upregulate SPNS2 expression in hepatocellular carcinoma

D Wang, M Li, H Shen, J Yang, Z Gao… - Biological Trace Element …, 2023 - Springer
Abstract The sphingosine-1-phosphate (S1P) transporter spinster homolog 2 (SPNS2)
promotes tumor progression by modulating tumor immunity and enhancing tumor cells …

Ectopic expression of matrix metalloproteinases and filopodia extension via JNK activation are involved in the invasion of blood tumor cells in Drosophila mxc mutant

K Takarada, J Kinoshita, YH Inoue - Genes to Cells, 2023 - Wiley Online Library
Drosophila mxc mbn1 mutant exhibits severe hyperplasia in larval hematopoietic tissue
called the lymph glands (LGs). However, the malignant nature of these cells remains …

Pan-cancer dissection of vasculogenic mimicry characteristic to provide potential therapeutic targets

H Tang, L Chen, X Liu, S Zeng, H Tan… - Frontiers in …, 2024 - frontiersin.org
Introduction: Vasculogenic mimicry (VM) represents a novel form of tumor angiogenesis that
is associated with tumor invasiveness and drug resistance. However, the VM landscape …

Plasma microRNA Signature as Companion Diagnostic for Abiraterone Acetate Treatment in Metastatic Castration-Resistant Prostate Cancer: A Pilot Study

S Detassis, F Precazzini, M Grasso… - International Journal of …, 2024 - mdpi.com
Abiraterone acetate (AA) serves as a medication for managing persistent testosterone
production in patients with metastatic castration-resistant prostate cancer (mCRPC) …

Leptin Promotes Vasculogenic Mimicry in Breast Cancer Cells by Regulating Aquaporin-1

DS Han, EO Lee - International Journal of Molecular Sciences, 2024 - mdpi.com
Leptin is an obesity-related hormone that plays an important role in breast cancer
progression. Vasculogenic mimicry (VM) refers to the formation of vascular channels lined …

Prostate Cancer Microvascular Routes: Exploration and Measurement Strategies

F Grizzi, MAAA Hegazi, M Zanoni, P Vota, G Toia… - Life, 2023 - mdpi.com
Angiogenesis is acknowledged as a pivotal feature in the pathology of human cancer.
Despite the absence of universally accepted markers for gauging the comprehensive …