A systematic review and meta-analysis of host genetic factors associated with influenza severity

N Van Goethem, C Danwang, N Bossuyt, H Van Oyen… - BMC genomics, 2021 - Springer
Background The severity of influenza disease can range from mild symptoms to severe
respiratory failure and can partly be explained by host genetic factors that predisposes the …

Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learning

BA Sokhansanj, GL Rosen - Computers in biology and medicine, 2022 - Elsevier
Epidemiological studies show that COVID-19 variants-of-concern, like Delta and Omicron,
pose different risks for severe disease, but they typically lack sequence-level information for …

Evolutionary analysis of seasonal influenza A viruses in Pakistan 2020–2023

N Badar, A Ikram, M Salman, S Saeed… - Influenza and Other …, 2024 - Wiley Online Library
Introduction Influenza A viruses cause global health concerns due to their high amino acid
substitution rates. They are linked to yearly seasonal epidemics and occasional pandemics …

Whole-genome sequence approach and phylogenomic stratification improve the association analysis of mutations with patient data in influenza surveillance

L Van Poelvoorde, K Vanneste… - Frontiers in …, 2022 - frontiersin.org
Each year, seasonal influenza results in high mortality and morbidity. The current
classification of circulating influenza viruses is mainly focused on the hemagglutinin gene …

[PDF][PDF] Exploring the added value of Whole Genome Sequencing in routine and pandemic viral surveillance

L Van Poelvoorde - 2023 - backoffice.biblio.ugent.be
Whole genome sequencing (WGS) has opened up a lot of new possibilities for virus
surveillance, however, many applications have remained unexploited in the context of …

[PDF][PDF] INFLUENZA VACCINE INDUCED ANTIBODY RESPONSES IN RELATION TO EVOLUTION OF INFLUENZA A VIRUSES

A Haveri - utupub.fi
Influenza A viruses (IAVs) cause yearly epidemics and occasionally appearing new
pandemics. IAVs are subtyped based on their virion surface glycoproteins haemagglutinin …