Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

MS Putman, AW Norris, RL Hull, MR Rickels… - Diabetes …, 2023 - Am Diabetes Assoc
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the
cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in …

Animal models of cystic fibrosis in the era of highly effective modulator therapies

BR Grubb, A Livraghi-Butrico - Current opinion in pharmacology, 2022 - Elsevier
Few human genetic diseases can rely on the availability of as many and as diverse animal
models as cystic fibrosis (CF), a multiorgan syndrome caused by functional absence of cystic …

CFTR-beyond the Airways: Recent Findings on the Role of the CFTR Channel in the Pancreas, the Intestine and the Kidneys

P Hegyi, U Seidler, K Kunzelmann - Journal of Cystic Fibrosis, 2023 - Elsevier
With increased longevity of patients suffering from cystic fibrosis, and widespread lung
transplantation facilities, the sequelae of defective CFTR in other organs than the airways …

[HTML][HTML] Fundamental and translational research in Cystic Fibrosis–why we still need it

CM Farinha, JL Brodsky, N Pedemonte - Journal of Cystic Fibrosis, 2023 - Elsevier
Clinical treatments for cystic fibrosis (CF) underwent significant changes in the last decade
as therapies targeting the basic defect in the CFTR protein were approved. Significant …

Design and fabrication of microfluidic-based 3d microphysiological systems for studying cell migration and invasion behaviors

X Wang, Q He, Q Li, Y Li, S Suresh… - … of Biomaterials and …, 2021 - ingentaconnect.com
The cell migration and invasion behaviors play pivotal roles in tissue regeneration. For the
skin repair process, a directed inflammatory response that regulates fibroblasts is critical for …