[HTML][HTML] Effects of titanium dioxide nanoparticles exposure on human health—a review

E Baranowska-Wójcik, D Szwajgier… - Biological trace element …, 2020 - Springer
Recently, an increased interest in nanotechnology applications can be observed in various
fields (medicine, materials science, pharmacy, environmental protection, agriculture etc.) …

Rethinking Nano‐TiO2 Safety: Overview of Toxic Effects in Humans and Aquatic Animals

Z Luo, Z Li, Z Xie, IM Sokolova, L Song… - Small, 2020 - Wiley Online Library
Titanium dioxide nanoparticles (nano‐TiO2) are widely used in consumer products, raising
environmental and health concerns. An overview of the toxic effects of nano‐TiO2 on human …

[HTML][HTML] Critical review of the safety assessment of titanium dioxide additives in food

HC Winkler, T Notter, U Meyer, H Naegeli - Journal of nanobiotechnology, 2018 - Springer
Nanomaterial engineering provides an important technological advance that offers
substantial benefits for applications not only in the production and processing, but also in the …

Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

EFSA Scientific Committee, A Hardy, D Benford… - EFSA …, 2018 - Wiley Online Library
Abstract The European Food Safety Authority has produced this Guidance on human and
animal health aspects (Part 1) of the risk assessment of nanoscience and nanotechnology …

[HTML][HTML] Detection of titanium particles in human liver and spleen and possible health implications

MB Heringa, RJB Peters, R Bleys… - Particle and fibre …, 2018 - Springer
Abstract Background Titanium dioxide (TiO 2) is produced at high volumes and applied in
many consumer and food products. Recent toxicokinetic modelling indicated the potential of …

[HTML][HTML] Possible adverse effects of food additive E171 (titanium dioxide) related to particle specific human toxicity, including the immune system

NS Bischoff, TM de Kok, DTHM Sijm… - International journal of …, 2020 - mdpi.com
Titanium dioxide (TiO2) is used as a food additive (E171) and can be found in sauces,
icings, and chewing gums, as well as in personal care products such as toothpaste and …

[HTML][HTML] Risk assessment frameworks for nanomaterials: Scope, link to regulations, applicability, and outline for future directions in view of needed increase in …

AG Oomen, KG Steinhäuser, EAJ Bleeker… - NanoImpact, 2018 - Elsevier
The increasing application of nanomaterials and the notion that their distinct features
compared to larger sized counterparts should be considered in safety assessment, has led …

Continuous in vitro exposure of intestinal epithelial cells to E171 food additive causes oxidative stress, inducing oxidation of DNA bases but no endoplasmic reticulum …

M Dorier, D Béal, C Marie-Desvergne… - …, 2017 - Taylor & Francis
The whitening and opacifying properties of titanium dioxide (TiO2) are commonly exploited
when it is used as a food additive (E171). However, the safety of this additive can be …

[HTML][HTML] Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental …

A Guillard, E Gaultier, C Cartier, L Devoille… - Particle and Fibre …, 2020 - Springer
Abstract Background Titanium dioxide (TiO 2) is broadly used in common consumer goods,
including as a food additive (E171 in Europe) for colouring and opacifying properties. The …

Possible effects of titanium dioxide particles on human liver, intestinal tissue, spleen and kidney after oral exposure

W Brand, RJB Peters, HM Braakhuis… - …, 2020 - Taylor & Francis
Recent studies reported adverse liver effects and intestinal tumor formation after oral
exposure to titanium dioxide (TiO2). Other oral toxicological studies, however, observed no …