[HTML][HTML] Effects of morphology and size of nanoscale drug carriers on cellular uptake and internalization process: a review

W Zhang, R Taheri-Ledari, F Ganjali… - RSC …, 2023 - pubs.rsc.org
In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

From autocatalysis to survival of the fittest in self-reproducing lipid systems

MG Howlett, SP Fletcher - Nature Reviews Chemistry, 2023 - nature.com
Studying autocatalysis—in which molecules catalyse their own formation—might help to
explain the emergence of chemical systems that exhibit traits normally associated with …

[HTML][HTML] Self-supervised machine learning pushes the sensitivity limit in label-free detection of single proteins below 10 kDa

M Dahmardeh, H Mirzaalian Dastjerdi, H Mazal… - Nature …, 2023 - nature.com
Interferometric scattering (iSCAT) microscopy is a label-free optical method capable of
detecting single proteins, localizing their binding positions with nanometer precision, and …

Operando monitoring of single-particle kinetic state-of-charge heterogeneities and cracking in high-rate Li-ion anodes

AJ Merryweather, Q Jacquet, SP Emge… - Nature Materials, 2022 - nature.com
To rationalize and improve the performance of newly developed high-rate battery electrode
materials, it is crucial to understand the ion intercalation and degradation mechanisms …

Nuclear export of circular RNA

LH Ngo, AG Bert, BK Dredge, T Williams, V Murphy… - Nature, 2024 - nature.com
Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions
in normal and cancerous cells,,,–, are formed by back-splicing of precursor mRNAs in the …

Single-molecule optical biosensing: recent advances and future challenges

S Dey, M Dolci, P Zijlstra - ACS Physical Chemistry Au, 2023 - ACS Publications
In recent years, the sensitivity and specificity of optical sensors has improved tremendously
due to improvements in biochemical functionalization protocols and optical detection …

Single-Molecule Spectroscopy and Super-Resolution Mapping of Physicochemical Parameters in Living Cells

MA Steves, C He, K Xu - Annual Review of Physical Chemistry, 2024 - annualreviews.org
By superlocalizing the positions of millions of single molecules over many camera frames, a
class of super-resolution fluorescence microscopy methods known as single-molecule …

Dual-angle interferometric scattering microscopy for optical multiparametric particle characterization

E Olsén, B García Rodríguez, F Skärberg… - Nano Letters, 2024 - ACS Publications
Traditional single-nanoparticle sizing using optical microscopy techniques assesses size via
the diffusion constant, which requires suspended particles to be in a medium of known …

Spinning disk interferometric scattering confocal microscopy captures millisecond timescale dynamics of living cells

YT Hsiao, TY Wu, BK Wu, SW Chu, CL Hsieh - Optics Express, 2022 - opg.optica.org
Interferometric scattering (iSCAT) microscopy is a highly sensitive imaging technique that
uses common-path interferometry to detect the linear scattering fields associated with …

Surface passivation with a perfluoroalkane brush improves the precision of single-molecule measurements

CJ Bueno-Alejo, M Santana Vega… - … Applied Materials & …, 2022 - ACS Publications
Single-molecule imaging is invaluable for investigating the heterogeneous behavior and
interactions of biological molecules. However, an impediment to precise sampling of single …