[HTML][HTML] Pathophysiological insight into fatty acid-binding protein-4: multifaced roles in reproduction, pregnancy, and offspring health

Y Shi, CC Wang, L Wu, Y Zhang, A Xu… - International Journal of …, 2023 - mdpi.com
Fatty acid-binding protein-4 (FABP4), commonly known as adipocyte-fatty acid-binding
protein (A-FABP), is a pleiotropic adipokine that broadly affects immunity and metabolism. It …

[HTML][HTML] Adipokines in pregnancy: A systematic review of clinical data

N Kabbani, M Blüher, H Stepan, M Stumvoll, T Ebert… - Biomedicines, 2023 - mdpi.com
Adipokines are signaling proteins involved in metabolic, endocrinological, vascular and
immunogenic processes. Associations of various adipokines with not only insulin resistance …

Adipokines in glucose and lipid metabolism

X Wang, S Zhang, Z Li - Adipocyte, 2023 - Taylor & Francis
Adipokines are proteins secreted by adipose tissue to regulate glucolipid metabolism and
play vital roles in our body. Different adipokines have more than one endocrine function and …

Adipose tissue‐derived FABP4 mediates glucagon‐stimulated hepatic glucose production in gestational diabetes

I Ron, R Mdah, R Zemet, RY Ulman… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims One of the most common complications of pregnancy is gestational diabetes mellitus
(GDM), which may result in significant health threats of the mother, fetus and the newborn …

[HTML][HTML] Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced Parkinson's …

H Weng, W Song, K Fu, Y Guan, G Cai… - Frontiers in …, 2023 - frontiersin.org
Introduction Parkinson's disease (PD), as a common neurodegenerative disease, currently
has no effective therapeutic approaches to delay or stop its progression. There is an urgent …

[HTML][HTML] Cord blood fatty acid binding protein 4 and lipids in infants born small-or large-for-gestational-age

X Liu, T Zheng, MY Tao, R Huang, GH Zhang… - Frontiers in …, 2023 - frontiersin.org
Aim Adverse (poor or excessive) fetal growth “programs” an elevated risk of type 2 diabetes.
Fatty acid binding protein 4 (FABP4) has been implicated in regulating insulin sensitivity and …

An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease

MF Burak, G Tuncman, AN Ayci, K Chetal… - bioRxiv, 2024 - biorxiv.org
Obesity-related airway disease is a clinical condition without a clear description and
effective treatment. Here, we define this pathology and its unique properties, which differ …

[HTML][HTML] Sympathetic tone dictates the impact of lipolysis on FABP4 secretion

KJ Prentice, A Lee, P Cedillo, KE Inouye… - Journal of Lipid …, 2023 - ASBMB
Levels of circulating fatty acid binding protein 4 (FABP4) protein are strongly associated with
obesity and metabolic disease in both mice and humans, and secretion is stimulated by β …