Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria
for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology …

The past 50years have seen rapid development of new building materials, furnishings, and
consumer products and a corresponding explosion in new chemicals in the built …

Background Many phthalates and phenols are hormonally active and are suspected to alter
the course of development. Objective We investigated prenatal exposures to phthalate and …

Phthalate esters are widely used as plasticizers in the manufacture of products made of
polyvinyl chloride. Mono-(2-ethylhexyl)-phthalate (MEHP) induces rodent …

Several therapeutic agents and industrial chemicals induce liver tumors in rodents through
the activation of the peroxisome proliferator-activated receptor alpha (PPARα). The cellular …

A number of industrial chemicals and therapeutic agents cause liver tumors in rats and mice
by activating the nuclear receptor peroxisome proliferator-activated receptor α (PPARα). The …

Background: Di (2-ethylhexyl) phthalate (DEHP) and its metabolites are known to affect lipid
metabolism and adipogenesis, mainly by activation of peroxisome proliferator-activated …

Diethyl phthalate (DEP), dibutyl phthalate (DBP) and butyl paraben (BP) are man‐made
chemicals used in personal care products, such as lotions and creams. Exposure to these …

Background: The observed age of menarche has fallen, which may have important adverse
social and health consequences. Increased exposure to endocrine-disrupting compounds …