[HTML][HTML] Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

[HTML][HTML] Obstacles to glioblastoma treatment two decades after temozolomide

JVR Cruz, C Batista, BH Afonso, MS Alexandre-Moreira… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastomas are the most common and aggressive brain tumors in
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …

An investigation into the effects of outer membrane vesicles and lipopolysaccharide of Porphyromonas gingivalis on blood-brain barrier integrity, permeability, and …

AB Pritchard, Z Fabian, CL Lawrence… - Journal of …, 2022 - content.iospress.com
Background: The effects of the key pathogens and virulence factors associated with gum
disease such as Porphyromonas gingivalis (P. gingivalis) on the central nervous system is of …

[HTML][HTML] Lipid nanostructures for targeting brain cancer

H Nsairat, D Khater, F Odeh, F Al-Adaileh, S Al-Taher… - Heliyon, 2021 - cell.com
Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …

[HTML][HTML] Tetrahydrocurcumin lipid nanoparticle based gel promotes penetration into deeper skin layers and alleviates atopic dermatitis in 2, 4-dinitrochlorobenzene …

K Saini, N Modgill, KK Singh, V Kakkar - Nanomaterials, 2022 - mdpi.com
Treatment of atopic dermatitis (AD) is challenging due to its complex pathophysiology.
Tetrahydrocurcumin (THC) a polyphenolic, colorless compound that is more polar than …

[HTML][HTML] Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis

M Soni, M Handa, KK Singh, R Shukla - Journal of Controlled Release, 2022 - Elsevier
COVID-19 acquired symptoms have affected the worldwide population and increased the
load of Intensive care unit (ICU) patient admissions. A large number of patients admitted to …

Mitocytosis Mediated by an Enzyme‐Activable Mitochondrion‐Disturbing Polymer‐Drug Conjugate Enhances Active Penetration in Glioblastoma Therapy

Y Xiang, B Wang, W Yang, X Zheng, R Chen… - Advanced …, 2024 - Wiley Online Library
The application of nanomedicines for glioblastoma (GBM) therapy is hampered by the blood–
brain barrier (BBB) and the dense glioblastoma tissue. To achieve efficient BBB crossing …

[HTML][HTML] Docetaxel loaded in copaiba oil-nanostructured lipid carriers as a promising DDS for breast cancer treatment

FV Carvalho, LNM Ribeiro, LD Moura… - Molecules, 2022 - mdpi.com
Breast cancer is the neoplasia of highest incidence in women worldwide. Docetaxel (DTX), a
taxoid used to treat breast cancer, is a BCS-class-IV compound (low oral bioavailability …

Drug delivery in glioblastoma therapy: a review on nanoparticles targeting MGMT-mediated resistance

ID Torres, JA Loureiro, MAN Coelho… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Glioblastoma multiforme (GBM) is the deadliest type of brain cancer with poor
response to the available therapies, mainly due to intrinsic resistance mechanisms …

[HTML][HTML] Antineoplastics encapsulated in nanostructured lipid carriers

GH Rodrigues da Silva, LD Moura, FV Carvalho… - Molecules, 2021 - mdpi.com
Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing
systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays …