[HTML][HTML] Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …
the pharmaceutical industry with the development of novel drug delivery systems that …
[HTML][HTML] Obstacles to glioblastoma treatment two decades after temozolomide
JVR Cruz, C Batista, BH Afonso, MS Alexandre-Moreira… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastomas are the most common and aggressive brain tumors in
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …
An investigation into the effects of outer membrane vesicles and lipopolysaccharide of Porphyromonas gingivalis on blood-brain barrier integrity, permeability, and …
AB Pritchard, Z Fabian, CL Lawrence… - Journal of …, 2022 - content.iospress.com
Background: The effects of the key pathogens and virulence factors associated with gum
disease such as Porphyromonas gingivalis (P. gingivalis) on the central nervous system is of …
disease such as Porphyromonas gingivalis (P. gingivalis) on the central nervous system is of …
[HTML][HTML] Lipid nanostructures for targeting brain cancer
Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …
[HTML][HTML] Tetrahydrocurcumin lipid nanoparticle based gel promotes penetration into deeper skin layers and alleviates atopic dermatitis in 2, 4-dinitrochlorobenzene …
Treatment of atopic dermatitis (AD) is challenging due to its complex pathophysiology.
Tetrahydrocurcumin (THC) a polyphenolic, colorless compound that is more polar than …
Tetrahydrocurcumin (THC) a polyphenolic, colorless compound that is more polar than …
[HTML][HTML] Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis
COVID-19 acquired symptoms have affected the worldwide population and increased the
load of Intensive care unit (ICU) patient admissions. A large number of patients admitted to …
load of Intensive care unit (ICU) patient admissions. A large number of patients admitted to …
Mitocytosis Mediated by an Enzyme‐Activable Mitochondrion‐Disturbing Polymer‐Drug Conjugate Enhances Active Penetration in Glioblastoma Therapy
The application of nanomedicines for glioblastoma (GBM) therapy is hampered by the blood–
brain barrier (BBB) and the dense glioblastoma tissue. To achieve efficient BBB crossing …
brain barrier (BBB) and the dense glioblastoma tissue. To achieve efficient BBB crossing …
[HTML][HTML] Docetaxel loaded in copaiba oil-nanostructured lipid carriers as a promising DDS for breast cancer treatment
FV Carvalho, LNM Ribeiro, LD Moura… - Molecules, 2022 - mdpi.com
Breast cancer is the neoplasia of highest incidence in women worldwide. Docetaxel (DTX), a
taxoid used to treat breast cancer, is a BCS-class-IV compound (low oral bioavailability …
taxoid used to treat breast cancer, is a BCS-class-IV compound (low oral bioavailability …
Drug delivery in glioblastoma therapy: a review on nanoparticles targeting MGMT-mediated resistance
ID Torres, JA Loureiro, MAN Coelho… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Glioblastoma multiforme (GBM) is the deadliest type of brain cancer with poor
response to the available therapies, mainly due to intrinsic resistance mechanisms …
response to the available therapies, mainly due to intrinsic resistance mechanisms …
[HTML][HTML] Antineoplastics encapsulated in nanostructured lipid carriers
GH Rodrigues da Silva, LD Moura, FV Carvalho… - Molecules, 2021 - mdpi.com
Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing
systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays …
systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays …